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MBP/MBL Protein (AA 21-248) (His tag)

MBP/MBL Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2181498
  • Target See all MBP/MBL Proteins
    MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-248
    Origin
    Human
    Source
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This MBP/MBL protein is labelled with His tag.
    Sequence
    AA 21-248
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.8 kDa. The protein migrates as 30-33 kDa under reducing (R) condition (SDS-PAGE).
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))
    Alternative Name
    MBL (MBP/MBL Products)
    Synonyms
    COLEC1 Protein, HSMBPC Protein, MBL Protein, MBL2D Protein, MBP Protein, MBP-C Protein, MBP1 Protein, MBPD Protein, pMBP-27 Protein, MBL1 Protein, cMBl Protein, collectin Protein, L-MBP Protein, MBL-C Protein, RaRF p28A Protein, mbl Protein, mannose binding lectin 2 Protein, mannose-binding lectin (protein C) 2 Protein, mannose-binding protein C-like Protein, MBL2 Protein, Mbl2 Protein, LOC100911854 Protein
    Background
    Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.
    Molecular Weight
    25.9 kDa
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