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MLH3 Products

(MutL Homolog 3 (MLH3))

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This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].

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Featured MLH3 Categories

MLH3 Antibodies

High quality antibodies with extensive validation data.

MLH3 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended MLH3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6259107
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, FACS
Validations
  • (2)
Cat. No. ABIN184792
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7183817
Quantity 100 μL
Datasheet Datasheet

Recommended MLH3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957922
Quantity 96 tests
Datasheet Datasheet

Recommended MLH3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3093827
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MLH3 products

Lipkin, Wang, Jacoby, Banerjee-Basu, Baxevanis, Lynch, Elliott, Collins: "MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability." in: Nature genetics, Vol. 24, Issue 1, pp. 27-35, (2000) (PubMed).

Synonyms and alternative names related to MLH3

mutL homolog 3 (Mlh3), mutL homolog 3 L homeolog (mlh3.L), mutL homolog 3 (MLH3), mutL homolog 3 (mlh3), AV125803, BB126472, HNPCC7, MGC80774, MLH3

Protein level used designations for MLH3

  • DNA mismatch repair protein Mlh3
  • mutL 3
  • mutL homolog 3
  • mutL homolog 3 (E. coli)
  • DNA mismatch repair protein Mlh3-like
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