anti-Human ATP-Binding Cassette, Sub-Family D (Ald), Member 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ATP-Binding Cassette, Sub-Family D (Ald), Member 1 Antibody (supplied by: Log in to see )

Antigen
ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) Antibodies
  • zgc:172102
  • ABCD1
  • ABC42
  • ALD
  • ALDP
  • AMN
  • Ald
  • Aldgh
  • RGD1562128
  • F2G19.18
  • F2G19_18
  • WPP domain protein 2
  • ATP binding cassette subfamily D member 1 L homeolog
  • ATP binding cassette subfamily D member 1
  • ATP-binding cassette, sub-family D (ALD), member 1
  • ATP-binding cassette sub-family D member 1
  • WPP domain protein 2
  • abcd1.L
  • ABCD1
  • abcd1
  • CpipJ_CPIJ013253
  • VDBG_05717
  • Abcd1
  • WPP2
Epitope
AA 264-293, Middle Region
7
5
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
31
4
2
1
1
Host
Rabbit
19
10
3
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
28
16
13
9
8
3
2
1
Supplier
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Catalog No. ABIN950202
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN962035 IHC (p) Rabbit IgG Log in to see Polyclonal 0
1 ABIN2615775 IHC (p) WB Mouse IgG2a AA 508-745 Log in to see 4C2 0
1 ABIN2615773 IHC (p) WB Mouse IgG2a AA 508-745 Log in to see 4E2 0
1 ABIN2615774 IHC (p) WB Mouse IgG2a AA 508-745 Log in to see 2C12 0
1 ABIN2615777 IHC (p) WB Mouse IgG2a AA 508-745 Log in to see 5G6 0
1 ABIN2880822 FACS IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1805530 FACS IHC (p) WB Rabbit AA 257-285 Log in to see Polyclonal 0
1 ABIN2768687 IHC (p) WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) Antibodies
Epitope AA 264-293, Middle Region
(7), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(31), (4), (2), (1), (1)
Host Rabbit
(19), (10), (3)
Clonality
Polyclonal
Conjugate Un-conjugated
(1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(28), (16), (13), (9), (8), (3), (2), (1)
Pubmed 3 references available
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Product details

Target Details Application Details Handling References Images
Specificity This antibody reacts to ABCD1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 264-293 amino acids from the Central region of human ABCD1.
Isotype Ig Fraction

Target Details

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Antigen
Alternative Name ABCD1 / ALDP (ABCD1 Antibody Abstract)
Background ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.Synonyms: ATP-binding cassette sub-family D member 1
Gene ID 215
NCBI Accession NP_000024
Pathways Monocarboxylic Acid Catabolic Process

Application Details

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Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References

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Background publications

Xie, Ke, Wang, Huang, Lan: "[A novel missense mutation resulting in X-linked adrenoleukodystrophy in female heterozygotes of a Chinese family]." in: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 27, Issue 2, pp. 144-8, 2010

Shukla, Gupta, Kabra, Ghosh, Sharma, Gupta, Gulati, Kalra: "Three novel variants in X-linked adrenoleukodystrophy." in: Journal of child neurology, Vol. 24, Issue 7, pp. 857-60, 2009

Sayeed, Mascreen, Arjundas, Valmikinathan: "Plasma lactate in anterior horn cell disease." in: Journal of the neurological sciences, Vol. 29, Issue 1, pp. 1-7, 1976

Images

Product details Target Details Application Details Handling References back to top
Supplier Images
Flow Cytometry (FACS) image for anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) (AA 264-293), (Middle Region) antibody (ABIN950202) ABCD1 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) com...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) (AA 264-293), (Middle Region) antibody (ABIN950202) ABCD1 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin ...
Western Blotting (WB) image for anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) (AA 264-293), (Middle Region) antibody (ABIN950202) ABCD1 Antibody (Center) western blot analysis in HL-60 cell line lysates (35 µg/lane)...