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Like in adults, FABP (show FABP2 Proteins) seems to be associated with markers of metabolic risk in obese adolescents
Data suggest that, in context of abnormal hepatic lipid accumulation in nonalcoholic fatty liver disease, circulating GOT2 rises due to up-regulation of hepatic expression of GOT2 associated with greater gluconeogenesis and insulin (show INS Proteins) resistance.
A previously unknown mechanism by which GOT2 acetylation stimulates the malate-aspartate NADH shuttle activity and oxidative protection.
The lipid binding process in L-FABP is associated with backbone dynamics.
PTLP activity is positively associated with serum ALT1 (show ALT Proteins), GOT1 (show GOT1 Proteins) and GOT2 in type 2 diabetes mellitus and metabolic syndrome.
Thermal aggregation of aspartate aminotransferase from pig heart mitochondria (mAAT) has been studied at various temperatures and various protein concentrations by dynamic light scattering.
GOT2-mediated ATP synthesis may be a pivotal mechanism underlying the protective effect of febuxostat against neurodegeneration in EA
it is quite likely that the down regulation of GOT2 after blast exposure is playing a significant role in mitochondrial dysfunction after blast exposure
The role of mAspAT in vivo is to control the levels of endogenous kynurenic acid (KYNA) through modulation of the mAspAt in the mouse brain.
KAT (show NEK1 Proteins) IV inhibited by equimolar tryptophan and aspartate, and half-life is 6.5 minutes at 65 degree C.
FAT/CD36 (show CD36 Proteins) and FABPpm protein content was increased in red muscles in IL-6 (show IL6 Proteins)(-/-) mice compared to WT mice at 4 (RG) and 12 months (soleus and RG).
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
, aspartate aminotransferase 2
, aspartate aminotransferase, mitochondrial
, aspartate transaminase 2
, fatty acid-binding protein
, glutamate oxaloacetate transaminase 2
, glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
, kynurenine aminotransferase 4
, kynurenine aminotransferase IV
, kynurenine--oxoglutarate transaminase 4
, kynurenine--oxoglutarate transaminase IV
, plasma membrane-associated fatty acid-binding protein
, transaminase A
, mitochondrial aspartate aminotransferase
, plasma membrane fatty acid binding protein
, Glutamate oxaloacetate transaminase 2, mitochondrial (aspartate aminotransferase 2)
, aspartate aminotransferase 2a
, glutamate oxaloacetate transaminase 2, mitochondrial