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neonatal Fc Receptor Proteins

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

Active filters:

  • Target: FcRn
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7866698
FcRn Protein (AA 24-297) (His tag) FcRn · Protein Human HEK-293 Cells
$735.38 View price
  • 50 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN7950699
FcRn Protein (His tag) FcRn · Protein Mouse Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
$478.00 View price
  • 100 μg
  • 1 mg
  • 50 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7943515
FcRn Protein (His tag) FcRn · Protein Human Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
$478.00 View price
  • 100 μg
  • 1 mg
  • 50 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN2720991
FcRn Protein (Transcript Variant 2) FcRn · Protein Human HEK-293 Cells
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
$402.00 View price
  • 10 μg
Delivery in 4 to 9 Business Days Shipping to: United States
Protein
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7866698
$735.38
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN7950699
$478.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN7943515
$478.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2720991
$402.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days

Latest Publications for our neonatal Fc Receptor Proteins

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." in: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." in: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." in: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." in: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." in: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." in: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." in: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Aliases for neonatal Fc Receptor Proteins

Fc fragment of IgG receptor and transporter (FCGRT) Proteins
Fc fragment of IgG receptor and transporter (Fcgrt) Proteins
Fc receptor, IgG, alpha chain transporter (Fcgrt) Proteins
alpha-chain Proteins
FCRN Proteins
FcRn Proteins
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