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|Antigen||Chromogranin A (CHGA) Antibodies|
|Reactivity||Human, Pig (Porcine) Alternatives|
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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|Immunogen||Pancreastatin antibody was raised in rabbit using synthetic pancreastatin as the immunogen.|
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|Alternative Name||Pancreastatin (CHGA Antibody Abstract)|
|Background||Pancreastatin is a 49-residue peptide hormone that inhibits glucose-induced insulin release and exocrine pancreatic secretion. It was originally isolated from porcine pancreas, where it is colocalized with insulin, glucagon and somatostatin, but it is part of the sequence of chromogranin A and is thus found in tissues where the chromogranin gene is expressed, including most endocrine cells.|
|Pathways||Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling|
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IHC-F: 1:50, IHC-P: 1:50
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
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|Buffer||Supplied as whole antiserum containing 0.09 % NaN3.Dilute immediately before use with PBS or TBS.|
|Precaution of Use||This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.|