anti-Human Chromogranin A antibody for Immunohistochemistry (Frozen Sections)

Recommended Chromogranin A Antibody (supplied by: Log in to see )

Antigen
Chromogranin A (CHGA) Antibodies
  • fj05f09
  • si:dkey-177p2.2
  • wu:fj05f09
  • zgc:101749
  • zgc:56075
  • CHGA
  • ChrA
  • CGA
  • cgA
  • chromogranin A
  • uncharacterized CHGA
  • chga
  • CHGA
  • Chga
Epitope
AA 19-131
17
15
14
12
10
8
8
6
5
5
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
1004
317
259
206
167
123
12
11
6
5
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Host
Mouse
684
321
22
7
1
1
Clonality
Monoclonal
Conjugate
Un-conjugated
40
35
31
31
27
16
16
16
15
15
15
15
15
15
15
15
15
15
14
14
14
14
14
14
14
14
14
14
14
14
14
14
12
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
683
633
460
404
306
212
211
196
167
102
16
13
13
8
6
3
2
1
1
Supplier
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Catalog No. ABIN1106699
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN115294 IHC (fro) IHC (p) Rabbit C-Term Log in to see Polyclonal 1
1 ABIN768712 IHC IHC (fro) IHC (p) WB Mouse IgG1 Log in to see LK2H10 0
1 ABIN115295 IHC (fro) IHC (p) Rabbit C-Term Log in to see Polyclonal 0
1 ABIN4298377 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 488 Mouse IgG1 kappa Log in to see CGA-414 1
1 ABIN4298360 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Mouse IgG1 kappa Log in to see CGA-414 1
1 ABIN4298415 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 647 Mouse IgG1 kappa Log in to see LK2H10 0
1 ABIN2472987 IHC (fro) IHC (p) WB Mouse IgG1 Log in to see LK2H10 4
1 ABIN4298395 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see LK2H10-PHE5 0
1 ABIN4298398 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG Log in to see LK2H10-PHE5-CGA-414 0
1 ABIN4298366 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 kappa Log in to see LK2H10 0
1 ABIN4298369 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 kappa Log in to see SPM339 0
1 ABIN4298374 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 kappa Log in to see SPM585 0
1 ABIN345272 IHC IHC (fro) IHC (p) WB Mouse IgG1, kappa Log in to see LK2H10 0
1 ABIN345275 IHC IHC (fro) IHC (p) Mouse IgG1 Log in to see LK2H10-PHE5 0
1 ABIN345274 IF IHC IHC (fro) IHC (p) Mouse IgG1 Log in to see PHE5 0
1 ABIN470741 IF IHC IHC (fro) IHC (p) WB Mouse IgG1, kappa Log in to see LK2H10 0
1 ABIN4298445 FACS ICC IF IHC (fro) IHC (p) WB DyLight 405 Mouse IgG1 Log in to see LK2H10-PHE5 0
1 ABIN4298447 FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 405 Mouse IgG Log in to see LK2H10-PHE5-CGA-414 0
1 ABIN4298448 FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Mouse IgG Log in to see LK2H10-PHE5-CGA-414 0
1 ABIN4298450 FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 700 Mouse IgG Log in to see LK2H10-PHE5-CGA-414 0

General

Antigen Chromogranin A (CHGA) Antibodies
Epitope AA 19-131
(17), (15), (14), (12), (10), (8), (8), (6), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(1004), (317), (259), (206), (167), (123), (12), (11), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(684), (321), (22), (7), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate Un-conjugated
(40), (35), (31), (31), (27), (16), (16), (16), (15), (15), (15), (15), (15), (15), (15), (15), (15), (15), (14), (14), (14), (14), (14), (14), (14), (14), (14), (14), (14), (14), (14), (14), (12), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(683), (633), (460), (404), (306), (212), (211), (196), (167), (102), (16), (13), (13), (8), (6), (3), (2), (1), (1)
Pubmed 2 references available
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Product details

Target Details Application Details Handling References Images
Purification Protein-G affinity chromatography
Immunogen Recombinant human Chromogranin A (19-131aa) purified from E. coli
Clone 3A5
Isotype IgG1

Target Details

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Antigen
Alternative Name Chromogranin A (CHGA Antibody Abstract)
Background Chromogranin A (CGA) is the major member of the granin family of acidic secretory glycoproteins that are expressed in all endocrine and neuroendocrine cells. Chromogranin A regulates catecholamine storage and release through intracellular (vesiculogenic) and extracellular (catecholamine release-inhibitory) mechanisms. Chromogranin A also plays a role in targeting peptide hormones and neurotransmitters to granules of the regulated pathway by virtue of their ability to aggregate in the low- pH , high-calcium environment of the trans-Golgi network. Therefore, Chromogranin A represents a specific marker of neuroendocrine cells and tumours including pheochromocytomas.Synonyms: CHGA, CgA, Chromogranin-A, Pituitary secretory protein I, SP-I
Gene ID 1113
NCBI Accession NP_001266
UniProt P10645
Pathways Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling

Application Details

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Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1.0 mg/mL
Buffer Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References

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Background publications

Wen, Mahata, Cadman, Mahata, Ghosh, Mahapatra, Rao, Stridsberg, Smith, Mahboubi, Schork, OConnor, Hamilton: "Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology." in: American journal of human genetics, Vol. 74, Issue 2, pp. 197-207, 2004

Nobels, Kwekkeboom, Bouillon, Lamberts: "Chromogranin A: its clinical value as marker of neuroendocrine tumours." in: European journal of clinical investigation, Vol. 28, Issue 6, pp. 431-40, 1998

Images

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Supplier Images
 image for anti-Chromogranin A (CHGA) (AA 19-131) antibody (ABIN1106699) anti-Chromogranin A (CHGA) (AA 19-131) antibody
 image for anti-Chromogranin A (CHGA) (AA 19-131) antibody (ABIN1106699) anti-Chromogranin A (CHGA) (AA 19-131) antibody (Image 2)