anti-Rat (Rattus) EGFR antibody for Flow Cytometry

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • C-erb
  • CG10079
  • D-EGFR
  • D-Egf
  • DEGFR
  • DER
  • DER flb
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DEgfr
  • Degfr
  • Der
  • DmHD-33
  • Dmel\\CG10079
  • EFG-R
  • EGF-R
  • EGFR
  • EGFr
  • EGfr
  • EK2-6
  • Egf
  • Egf-r
  • EgfR
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • HD-33
  • TOP
  • Torpedo/DER
  • Torpedo/Egfr
  • c-erbB
  • d-egf-r
  • dEGFR
  • dEGFR1
  • dEgfr
  • der
  • egfr
  • flb
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57EFa
  • l(2)57Ea
  • mor1
  • top
  • top/DER
  • top/flb
  • torpedo/Egfr
  • torpedo/egfr
  • EGFR12
  • EGFR15
  • egfr1
  • Erbb2
  • ERBB
  • ERBB1
  • HER1
  • PIG61
  • mENA
  • ErbB-1
  • Errp
  • 9030024J15Rik
  • AI552599
  • Erbb
  • Errb1
  • Wa5
  • wa-2
  • wa2
  • epidermal growth factor receptor
  • Epidermal growth factor receptor
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • EGFR
  • Egfr
  • egfra
  • egfr1
  • LOC5564544
Epitope
pTyr1068
120
88
64
60
59
56
55
54
51
50
49
38
37
34
32
32
30
28
28
26
24
23
22
18
18
18
18
17
16
16
16
16
16
15
15
15
15
15
15
15
14
13
11
10
8
8
8
7
6
6
6
6
6
6
5
5
5
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
2438
873
744
29
27
20
19
16
14
7
4
3
2
2
2
2
2
2
2
1
1
1
1
Host
Rabbit
1498
858
75
24
14
5
2
1
1
Clonality
Monoclonal
Conjugate
This EGFR antibody is conjugated to SureLight 488®
97
73
70
63
53
46
44
29
26
24
23
22
21
21
21
21
21
21
21
20
19
19
19
19
19
19
17
17
15
8
8
8
8
8
8
8
8
8
8
8
8
8
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS)
1482
695
597
591
479
386
272
245
121
89
86
56
55
40
24
22
19
11
10
8
8
4
4
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN6390719
$ 460.31
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4 ABIN1854890 FACS IF/ICC WB Rabbit IgG N-Term Log in to see Polyclonal 0
4 ABIN1112884 ICC FACS WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1576216 ICC FACS WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Epitope pTyr1068
(120), (88), (64), (60), (59), (56), (55), (54), (51), (50), (49), (38), (37), (34), (32), (32), (30), (28), (28), (26), (24), (23), (22), (18), (18), (18), (18), (17), (16), (16), (16), (16), (16), (15), (15), (15), (15), (15), (15), (15), (14), (13), (11), (10), (8), (8), (8), (7), (6), (6), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(2438), (873), (744), (29), (27), (20), (19), (16), (14), (7), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(1498), (858), (75), (24), (14), (5), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This EGFR antibody is conjugated to SureLight 488®
(97), (73), (70), (63), (53), (46), (44), (29), (26), (24), (23), (22), (21), (21), (21), (21), (21), (21), (21), (20), (19), (19), (19), (19), (19), (19), (17), (17), (15), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS)
(1482), (695), (597), (591), (479), (386), (272), (245), (121), (89), (86), (56), (55), (40), (24), (22), (19), (11), (10), (8), (8), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling Images
Purification

Purification Method: Protein A+G

Purified From: Cell culture

Immunogen A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human phospho EGFR.
Clone EGFRY1068-E5
Isotype IgG1 kappa
Plasmids, Primers & others

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling Images back to top
Antigen
Alternative Name EGFR (EGFR Antibody Abstract)
Background The epidermal growth factor (EGFR, phospho EGFR), also known as ErbB1 and HER1, is a receptor tyrosine kinase (RTK) and a known oncogenic driver of several cancer types including lung cancer (1), breast cancer (2), and glioblastoma (3) and inhibitors of EGFR have been the most successful examples of targeted therapies including antibody therapeutics (e.g. trastuzumab and cetuximab) as well as small-molecule inhibitors erlotinib and lapatinib (4). Ligand binding induces multiple EGFR auto-phosphorylation including Tyr1068. This phosphorylation recruits growth factor receptor-bound protein 2 (Grb2) which mediates downstream modulation of EGFR signaling including activation of signaling cascades through interaction of Grb2 SH3 domains with the Ras guanine exchange factor, son of sevenless homolog (SOS) or downregulation of phospho EGFR signaling through internalization and ubiquitination-targeted degradation (5).
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details Images back to top
Buffer

Formulation: 1X PBS, 0.09 % Sodium azide, 0.2 % BSA

 pH : 7.4

Images

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Epidermal Growth Factor Receptor (EGFR) (pTyr1068) antibody (SureLight 488®) (ABIN6390719) Flow cytometric analysis of K562 cells unstained cells negative control (blue) or sta...