anti-Human Growth Hormone Receptor antibody for Western Blotting

Recommended Growth Hormone Receptor Antibody (supplied by: Log in to see )

Antigen
Growth Hormone Receptor (GHR) Antibodies
  • GHBP
  • AA986417
  • GHR/BP
  • GHR
  • ghr
  • growth hormone receptor
  • growth hormone receptor L homeolog
  • GHR
  • Ghr
  • ghr.L
  • ghr
Epitope
N-Term
15
8
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
67
39
36
17
2
2
1
1
1
1
Host
Rabbit
69
15
2
Clonality
Polyclonal
Conjugate
This Growth Hormone Receptor antibody is un-conjugated
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
53
30
13
13
12
7
5
3
3
2
2
1
1
1
1
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Catalog No. ABIN2781772
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2908103 ABIN2781773 WB Rabbit C-Term Log in to see Polyclonal 0
3.2908103 ABIN1981335 WB Rabbit IgG Log in to see Polyclonal 0
3.2908103 ABIN441424 IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal 1
3.2908103 ABIN1859006 ICC IHC WB Rabbit IgG AA 315-574 Log in to see Polyclonal 0
3.2908103 ABIN1872812 WB Rabbit IgG Log in to see Polyclonal 0
3.2908103 ABIN4893157 WB Rabbit N-Term Log in to see Polyclonal 0
3.2908103 ABIN635863 WB Rabbit N-Term Log in to see Polyclonal 0
3.2908103 ABIN3181426 ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
3.2908103 ABIN3017062 WB Rabbit Log in to see Polyclonal 0
1 ABIN671481 IF (p) IHC (p) WB Rabbit IgG AA 290-340 Log in to see Polyclonal 6
1 ABIN4900013 CyTOF FACS IHC Neut WB Goat IgG AA 27-264 Log in to see Polyclonal 2
1 ABIN4886601 IHC (p) WB Rabbit IgG AA 101-117, N-Term Log in to see Polyclonal 0
1 ABIN468960 WB Rabbit AA 36-85 Log in to see Polyclonal 0
1 ABIN4900012 FACS IHC WB Biotin Goat IgG AA 27-264 Log in to see Polyclonal 0
1 ABIN1495060 IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN395765 ELISA WB Mouse IgG2a kappa AA 19-119 Log in to see 3A12 0
1 ABIN1585686 IHC ELISA WB Rabbit Middle Region Log in to see Polyclonal 0
1 ABIN4965281 WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN671490 IHC (p) WB HRP Rabbit IgG AA 290-340 Log in to see Polyclonal 0
1 ABIN561042 PLA ELISA WB Mouse IgG2a kappa AA 19-118, partial Log in to see 3A12 0

General

Antigen Growth Hormone Receptor (GHR) Antibodies
Epitope N-Term
(15), (8), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(67), (39), (36), (17), (2), (2), (1), (1), (1), (1)
Host Rabbit
(69), (15), (2)
Clonality
Polyclonal
Conjugate This Growth Hormone Receptor antibody is un-conjugated
(3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(53), (30), (13), (13), (12), (7), (5), (3), (3), (2), (2), (1), (1), (1), (1)
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Product Details anti-Growth Hormone Receptor Antibody

Target Details Growth Hormone Receptor Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN977395
Sequence LQSVNPGLKT NSSKEPKFTK CRSPERETFS CHWTDEVHHG TKNLGPIQLF
Predicted Reactivity Human: 100%
Characteristics This is a rabbit polyclonal antibody against GHR. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human GHR

Target Details Growth Hormone Receptor

Product Details anti-Growth Hormone Receptor Antibody Application Details Handling Images back to top
Antigen
Alternative Name GHR (GHR Antibody Abstract)
Background GHR is a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GHBP
Protein Interaction Partner: FBXW11, JAK2, GHR, GH1, BTRC, UBC, SKP1, SOCS2, STUB1, PTPRH, PTPRB, PTPN13, PTPN9, PTPN3, PTPN2, PTPN1, DUSP7, NCOA6, STAT5B, SOCS3, SOCS1, SGTA, CISH, GRB10, STAT5A, AP2A1, SHC1, TYK2, PTPN6, PTPN11, PRLR, PIK3R1, JAK1, IRS1, GH2, GRB2, STAT3, PLCG1,
Protein Size: 638
Molecular Weight 70 kDa
Gene ID 2690
NCBI Accession NM_000163, NP_000154
UniProt P10912
Pathways NF-kappaB Signaling, JAK-STAT Signaling, Response to Growth Hormone Stimulus

Application Details

Product Details anti-Growth Hormone Receptor Antibody Target Details Growth Hormone Receptor Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 638 AA

Restrictions For Research Use only

Handling

Product Details anti-Growth Hormone Receptor Antibody Target Details Growth Hormone Receptor Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-Growth Hormone Receptor Antibody Target Details Growth Hormone Receptor Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Growth Hormone Receptor (GHR) (N-Term) antibody (ABIN2781772) anti-Growth Hormone Receptor (GHR) (N-Term) antibody