anti-Human NFKBIA antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended NFKBIA Antibody

Antigen
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Antibodies
  • IKBA
  • MAD-3
  • NFKBI
  • AI462015
  • Nfkbi
  • RL/IF-1
  • ECI-6/IKBA
  • ikbaA
  • wu:fj16a07
  • zgc:85769
  • NFKB inhibitor alpha
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
  • NFKBIA
  • Nfkbia
  • nfkbiaa
Epitope
AA 5-34
69
59
41
35
30
21
17
15
14
13
10
10
8
7
7
5
5
5
4
4
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
503
316
249
32
22
20
19
9
2
2
2
1
1
Host
Rabbit
446
64
7
7
Clonality
Polyclonal
Conjugate
This NFKBIA antibody is un-conjugated
24
13
13
13
13
13
13
10
9
6
6
6
3
3
3
3
3
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
354
175
175
81
70
61
40
21
19
18
18
7
6
4
3
1
1
1
Options

Available images

Catalog No. ABIN674454
$ 329.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
16 ABIN710696 IF (p) IHC (p) WB Rabbit IgG AA 295-310, pTyr305 Polyclonal 7
8.5 ABIN741360 IF (p) IHC (p) WB Rabbit IgG pSer32 Polyclonal 1
1 ABIN2804633 IF (p) Alexa Fluor 594 Rabbit IgG AA 5-34 Polyclonal 0
1 ABIN908223 IF (p) Alexa Fluor 350 Rabbit IgG AA 5-34 Polyclonal 0
1 ABIN908227 IF (p) Alexa Fluor 647 Rabbit IgG AA 5-34 Polyclonal 0
1 ABIN908224 IF (p) Alexa Fluor 488 Rabbit IgG AA 5-34 Polyclonal 0
1 ABIN908226 IF (p) Alexa Fluor 555 Rabbit IgG AA 5-34 Polyclonal 0
1 ABIN879417 IF (p) Alexa Fluor 350 Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN879418 IF (p) Alexa Fluor 555 Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN879415 IF (p) Alexa Fluor 647 Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN879414 IF (p) Alexa Fluor 488 Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN2804632 IF (p) Alexa Fluor 594 Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN710699 IF (p) Cy3 Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN710701 IF (p) Cy5.5 Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN710702 IF (p) Cy7 Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN710703 IF (p) FITC Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN710700 IF (p) Cy5 Rabbit IgG AA 295-310, pTyr305 Polyclonal 0
1 ABIN674458 IF (p) Cy5 Rabbit IgG AA 5-34 Polyclonal 0
1 ABIN674457 IF (p) Cy3 Rabbit IgG AA 5-34 Polyclonal 0
1 ABIN674459 IF (p) Cy5.5 Rabbit IgG AA 5-34 Polyclonal 0

General

Antigen Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Antibodies
Epitope AA 5-34
(69), (59), (41), (35), (30), (21), (17), (15), (14), (13), (10), (10), (8), (7), (7), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(503), (316), (249), (32), (22), (20), (19), (9), (2), (2), (2), (1), (1)
Host Rabbit
(446), (64), (7), (7)
Clonality
Polyclonal
Conjugate This NFKBIA antibody is un-conjugated
(24), (13), (13), (13), (13), (13), (13), (10), (9), (6), (6), (6), (3), (3), (3), (3), (3)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(354), (175), (175), (81), (70), (61), (40), (21), (19), (18), (18), (7), (6), (4), (3), (1), (1), (1)
Pubmed 12 references available
Supplier

Product Details anti-NFKBIA Antibody

Target Details NFKBIA Application Details Handling References for anti-NFKBIA antibody (ABIN674454) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse IKB alpha
Isotype IgG
Plasmids, Primers & others

Target Details NFKBIA

Product Details anti-NFKBIA Antibody Application Details Handling References for anti-NFKBIA antibody (ABIN674454) Images back to top
Antigen
Alternative Name Nfkbia/Ikb alpha (NFKBIA Antibody Abstract)
Background

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Subcellular location: Cytoplasm, Nucleus

Synonyms: Nfkbi, AI46215, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Nfkbia, Ikba

Gene ID 18035
UniProt Q9Z1E3
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades

Application Details

Product Details anti-NFKBIA Antibody Target Details NFKBIA Handling References for anti-NFKBIA antibody (ABIN674454) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-NFKBIA Antibody Target Details NFKBIA Application Details References for anti-NFKBIA antibody (ABIN674454) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-NFKBIA antibody (ABIN674454)

Product Details anti-NFKBIA Antibody Target Details NFKBIA Application Details Handling Images back to top
Product cited in:

Liu, Zhang, Han, Wang, Liu, Zhang, Zhou, Xiang: "Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 192-200, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: lung

Sun, Yang, Zhang, Zhao: "Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats." in: Experimental animals, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: kidney

Gao, Guo, Wang, Lin, Yu, Sheng, Wu, Gong: "Indirubin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice through the inhibition of inflammation and the induction of Foxp3-expressing regulatory T cells." in: Acta histochemica, Vol. 118, Issue 6, pp. 606-14, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)). Further details: Sample: colon

Zhao, Zheng, Hu, Shen, Li: "Betulin attenuates kidney injury in septic rats through inhibiting TLR4/NF-κB signaling pathway." in: Life sciences, Vol. 144, pp. 185-93, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: Kidney

Li, Zhang, Qi, Zhang, Yi, Li, Zhang: "Valproate ameliorates nitroglycerin-induced migraine in trigeminal nucleus caudalis in rats through inhibition of NF-кB." in: The journal of headache and pain, Vol. 17, pp. 49, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: Brain

Yu, Shi, Qi, Zhao, Gao, Li: "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." in: Frontiers in pharmacology, Vol. 7, pp. 148, 2016 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: ischemic penumbra

Yan, Wu, Li, Meng, Dai, Zheng, Fu: "Cyanidin-3-O-glucoside Induces Apoptosis and Inhibits Migration of Tumor Necrosis Factor-?-Treated Rat Aortic Smooth Muscle Cells." in: Cardiovascular toxicology, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Ma, Liu, Wang, Liu, Chen, Valle, Zuo, Xia, Liu: "Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals." in: ACS nano, Vol. 9, Issue 10, pp. 10498-515, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Yan, Wu, Li, Meng, Dai, Zheng, Fu: "Cyanidin-3-O-glucoside attenuates acute lung injury in sepsis rats." in: The Journal of surgical research, Vol. 199, Issue 2, pp. 592-600, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)). Further details: Sample: Lung

Zhao, Liu, Liu, Han, Zhao: "Betulin attenuates lung and liver injuries in sepsis." in: International immunopharmacology, Vol. 30, pp. 50-6, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: Lung

Yang, Wang, Zhang, Yang, Lu, Zhang, Li, Zhang, Li: "Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-?B signaling pathway in isoproterenol-induced myocardial hypertrophy." in: Journal of ethnopharmacology, Vol. 150, Issue 3, pp. 1062-70, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: left ventricle and neonatal cardiomyocytes

Jiang, Tian, Fu, Zhu, Hou: "Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury." in: European journal of pharmacology, Vol. 640, Issue 1-3, pp. 75-81, 2010 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: brain

Images

Product Details anti-NFKBIA Antibody Target Details NFKBIA Application Details Handling References for anti-NFKBIA antibody (ABIN674454) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 5-34) antibody (ABIN674454) Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti-NFKBIA/IKB a...
Western Blotting (WB) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 5-34) antibody (ABIN674454) Lane 1: Mouse Spleen lysates probed with NFKBIA/IKB alpha Polyclonal Antibody, Unconj...