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DTX2 is a gene encoding a WWE-RING-finger protein and involved in regulating heart development and heart functions.
It is reported that BBAP and the human family of DTX proteins (DTX1, DTX2, and DTX3) function as E3 ligases based on their capacity for self-ubiquitination.
Deltex can act as a negative regulator of Notch signals in T cells but that endogenous levels of Deltex1 and Deltex2 are not important for regulating Notch signals during thymocyte development
DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003
, probable E3 ubiquitin-protein ligase DTX2
, protein deltex-2
, ring finger protein 58
, zinc ion binding protein
, deltex 2 homolog
, deltex 2
, deltex homolog 2 (Drosophila)
, protein deltex-2-like
, deltex homolog 2