DTX2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all DTX2 Proteins
- DTX2 (Deltex Homolog 2 (DTX2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DTX2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human DTX2 / RNF58 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DTX2 Protein
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Deltex Homolog 2 (DTX2) (AA 1-622) protein (Strep Tag)
Crystallography grade DTX2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Deltex Homolog 2 (DTX2) (AA 1-619) protein (Strep Tag)Crystallography grade DTX2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Deltex Homolog 2 (DTX2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DTX2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Deltex Homolog 2 (DTX2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DTX2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DTX2 (Deltex Homolog 2 (DTX2))
- Alternative Name
- Dtx2,rnf58 (DTX2 Products)
- Synonyms
- RNF58 Protein, 2610524D08Rik Protein, AA408415 Protein, AU022494 Protein, Deltex2 Protein, dtx2 Protein, deltex E3 ubiquitin ligase 2 Protein, probable E3 ubiquitin-protein ligase DTX2 Protein, deltex 2, E3 ubiquitin ligase Protein, deltex 2, E3 ubiquitin ligase S homeolog Protein, DTX2 Protein, Dtx2 Protein, LOC735784 Protein, LOC747633 Protein, dtx2 Protein, dtx2.S Protein
- Background
- Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 67.1 kDa
- NCBI Accession
- NP_001096065
- Pathways
- Notch Signaling
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