anti-Pig (Porcine) NCOR2 antibody for Western Blotting

Recommended NCOR2 Antibody (supplied by: Log in to see )

Antigen
Nuclear Receptor Co-Repressor 2 (NCOR2) Antibodies
  • CTG26
  • N-CoR2
  • SMAP270
  • SMRT
  • SMRTE
  • SMRTE-tau
  • TNRC14
  • TRAC
  • TRAC-1
  • TRAC1
  • N-CoR
  • SMRTe
  • NCOR2
  • gb:be017685
  • si:bz71m17.2
  • smrt
  • ctg26
  • smrte
  • trac1
  • tnrc14
  • trac-1
  • smrte-tau
  • nuclear receptor corepressor 2
  • nuclear receptor co-repressor 2
  • NCOR2
  • Ncor2
  • ncor2
Epitope
N-Term
9
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Yeast (Saccharomyces cerevisiae), Zebrafish (Danio rerio)
79
26
24
4
3
3
2
1
1
Host
Rabbit
51
19
8
1
Clonality
Polyclonal
Conjugate
This NCOR2 antibody is un-conjugated
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
46
25
18
13
11
10
9
3
3
2
2
2
1
Options
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Catalog No. ABIN2779658
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1357021 ABIN2779659 WB Rabbit N-Term Log in to see Polyclonal 1
1 ABIN214126 IHC IHC (p) WB Rabbit IgG AA 511-560 Log in to see Polyclonal 0
1 ABIN202991 WB Rabbit IgG AA 541-590 Log in to see Polyclonal 0

General

Antigen Nuclear Receptor Co-Repressor 2 (NCOR2) Antibodies
Epitope N-Term
(9), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Yeast (Saccharomyces cerevisiae), Zebrafish (Danio rerio)
(79), (26), (24), (4), (3), (3), (2), (1), (1)
Host Rabbit
(51), (19), (8), (1)
Clonality
Polyclonal
Conjugate This NCOR2 antibody is un-conjugated
(3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(46), (25), (18), (13), (11), (10), (9), (3), (3), (2), (2), (2), (1)
Pubmed 1 reference available
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Product Details anti-NCOR2 Antibody

Target Details NCOR2 Application Details Handling References for anti-NCOR2 antibody (ABIN2779658) Images
Blocking Peptide Blocking peptide for this product available: ABIN980539
Sequence PMPRSSQEEK DEKEKEKEAE KEEEKPEVEN DKEDLLKEKT DDTSGEDNDE
Predicted Reactivity Cow: 93%, Dog: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 86%, Yeast: 87%, Zebrafish: 79%
Characteristics This is a rabbit polyclonal antibody against NCOR2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR2
Plasmids, Primers & others

Target Details NCOR2

Product Details anti-NCOR2 Antibody Application Details Handling References for anti-NCOR2 antibody (ABIN2779658) Images back to top
Antigen
Alternative Name NCOR2 (NCOR2 Antibody Abstract)
Background NCOR2 forms a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid (TR) and the retinoid acid receptors (RAR) in the absence of ligand, and may stabilize their interaction with TFIIB. NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Alias Symbols: SMRT, TRAC, CTG26, SMRTE, TRAC1, N-CoR2, TNRC14, TRAC-1, SMAP270, SMRTE-tau
Protein Interaction Partner: HDAC4, HDAC3, RARA, HMGA1, HDAC2, HDAC1, AURKA, BCL6, BCOR, GPS2, ZBTB16, UBC, E2F1, NR1I2, BTRC, HDAC7, NR1H2, THRA, RUNX1, Pparg, Nr2f1, Nr1i3, Nr2f2, CBX6, C1D, NR1H4, NR1D1, Ppard, SUMO2, CTBP1, ARNT, AHR, NCOR1, AR, NRD1, E2F4, ZBTB7A, SOX2, ESR1, CE
Protein Size: 2524
Molecular Weight 275 kDa
Gene ID 9612
NCBI Accession NM_006312, NP_006303
UniProt Q9Y618
Pathways Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha

Application Details

Product Details anti-NCOR2 Antibody Target Details NCOR2 Handling References for anti-NCOR2 antibody (ABIN2779658) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 2524 AA

Restrictions For Research Use only

Handling

Product Details anti-NCOR2 Antibody Target Details NCOR2 Application Details References for anti-NCOR2 antibody (ABIN2779658) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NCOR2 antibody (ABIN2779658)

Product Details anti-NCOR2 Antibody Target Details NCOR2 Application Details Handling Images back to top
Background publications

Keeton, Brown: "Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 6, pp. 1543-54, 2005

Images

Product Details anti-NCOR2 Antibody Target Details NCOR2 Application Details Handling References for anti-NCOR2 antibody (ABIN2779658) back to top
Supplier Images
Western Blotting (WB) image for anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (N-Term) antibody (ABIN2779658) WB Suggested Anti-NCOR2 Antibody Titration: 0.2-1 ug/ml Positive Control: Hela cel...
Western Blotting (WB) image for anti-Nuclear Receptor Co-Repressor 2 (NCOR2) (N-Term) antibody (ABIN2779658) WB Suggested Anti-NCOR2
Antibody Titration: 0.2-1 µg/mL
Positive Contro...