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OMA1 Zinc Metallopeptidase Homolog Products

(OMA1 Zinc Metallopeptidase Homolog (OMA1))
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions (By similarity).

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Featured OMA1 Zinc Metallopeptidase Homolog Categories

OMA1 Zinc Metallopeptidase Homolog Antibodies

High quality antibodies with extensive validation data.

OMA1 Zinc Metallopeptidase Homolog ELISA Kits

Reliable ELISA kits for a wide range of species.

OMA1 Zinc Metallopeptidase Homolog Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended OMA1 Zinc Metallopeptidase Homolog Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7159465
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (2)
  • (4)
Cat. No. ABIN2785108
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validations
  • (1)
Cat. No. ABIN5675734
Quantity 100 μL
Datasheet Datasheet

Recommended OMA1 Zinc Metallopeptidase Homolog ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1142216
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1142217
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1142215
Quantity 96 tests
Datasheet Datasheet

Recommended OMA1 Zinc Metallopeptidase Homolog Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313386
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our OMA1 Zinc Metallopeptidase Homolog products

Desmurs, Foti, Raemy, Vaz, Martinou, Bairoch, Lane: "C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization." in: Molecular and cellular biology, Vol. 35, Issue 7, pp. 1139-56, (2015) (PubMed).

Baburamani, Hurling, Stolp, Sobotka, Gressens, Hagberg, Thornton: "Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury." in: International journal of molecular sciences, Vol. 16, Issue 9, pp. 22509-26, (2015) (PubMed).

Kong, Tsuyoshi, Orisaka, Shieh, Yoshida, Tsang: "Mitochondrial dynamics regulating chemoresistance in gynecological cancers." in: Annals of the New York Academy of Sciences, Vol. 1350, pp. 1-16, (2015) (PubMed).

Bohovych, Fernandez, Rahn, Stackley, Bestman, Anandhan, Franco, Claypool, Lewis, Chan, Khalimonchuk: "Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability." in: Scientific reports, Vol. 5, pp. 13989, (2015) (PubMed).

Xiao, Hu, Quirós, Wei, López-Otín, Dong: "OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury." in: American journal of physiology. Renal physiology, Vol. 306, Issue 11, pp. F1318-26, (2014) (PubMed).

Kong, Wang, Fung, Xue, Tsang: "p53 is required for cisplatin-induced processing of the mitochondrial fusion protein L-Opa1 that is mediated by the mitochondrial metallopeptidase Oma1 in gynecologic cancers." in: The Journal of biological chemistry, Vol. 289, Issue 39, pp. 27134-45, (2014) (PubMed).

Bohovych, Donaldson, Christianson, Zahayko, Khalimonchuk: "Stress-triggered activation of the metalloprotease Oma1 involves its C-terminal region and is important for mitochondrial stress protection in yeast." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13259-72, (2014) (PubMed).

Synonyms and alternative names related to OMA1 Zinc Metallopeptidase Homolog

OMA1 zinc metallopeptidase (OMA1), OMA1 zinc metallopeptidase (Oma1), si:ch73-215a11.1 (si:ch73-215a11.1), olfactory receptor 4K2 (LOC531304), 2010001O09Rik, DAB1, MPRP-1, oma1, peptidase, RGD1304821, YKR087C, ZMPOMA1

Protein level used designations for OMA1 Zinc Metallopeptidase Homolog

  • OMA1 homolog, zinc metallopeptidase
  • OMA1 zinc metallopeptidase homolog
  • metalloendopeptidase OMA1, mitochondrial
  • metalloprotease related protein 1
  • metalloprotease-related protein 1
  • overlapping activity with M-AAA protease
  • overlapping with the m-AAA protease 1 homolog
  • zinc metallopeptidase OMA1
  • Metalloendopeptidase OMA1, mitochondrial
  • OMA1 zinc metallopeptidase
  • Overlapping with the m-AAA protease 1 homolog
  • olfactory receptor 4K2
  • Metalloendopeptidase OMA1, mitochondrial-like protein
  • metalloendopeptidase OMA1 mitochondrial-like protein
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