B7-H3 Detection Set (Risk Free)
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- Target See all CD276 products
- CD276
- Binding Specificity
- Extracellular Domain
- Reactivity
- Human
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Host
- Mouse
- Clonality
- Monoclonal
- Application
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- Brand
- Risk-Free™
- Characteristics
- B7-H3 Antibody: CD276, also known as B7-H3, was initially identified as a member of the B7 family of proteins through its homology with previously identified B7 Molecules (1). CD276 mRNA is widely expressed, but its protein expression is usually rather low (2). CD276 has been shown to play a role in both the costimulation as well as the coinhibition of T cell response (3). In a similar fashion, CD276 plays a critical role in the control of antitumor immune responses in some cases, while in others appears to mediate antitumor immunity (4). It thus joins other immune checkpoint proteins as a possible therapeutic target for at least a subset of cancers.
- Purification
- Antibodies are supplied as protein A purified IgG1
- Components
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B7-H3 Antibody [2H5]
B7-H3 Antibody [2A7]
B7-H3 Antibody [4H3]
B7-H3 Antibody [7B3]
B7-H3 Antibody [10G6] - Immunogen
- B7-H3 antibodies were raised against the extracellular domain of human B7-H3
- Isotype
- IgG1
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CD276 (Human) Matched Antibody Pair
ELISA Reactivity: Human ELISA unconjugated Host: Mouse
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- Comment
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Risk-Free™ antibodies are monoclonal antibodies made to improve in vitro studies.
Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein.
These antibodies have the following advantages:
- Antibodies are developed against mammalian-expressed, post-translationally modified recombinant proteins.
- Multiple antibodies per target allows the user to choose the best antibody for their application
- Available individually or as a set
- Risk-Free™ means they are rigorously tested and guaranteed to work for their designated applications:
- ELISA
- Flow Cytometry
- Immunoblot
- Immunohistochemistry
- Immunocytochemistry
- Immunofluorescence - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- CD276
- Alternative Name
- B7-H3 (CD276 Products)
- Synonyms
- sc:d0645 Matched Antibody Pair, zgc:158279 Matched Antibody Pair, 6030411F23Rik Matched Antibody Pair, AU016588 Matched Antibody Pair, B7RP-2 Matched Antibody Pair, B7h3 Matched Antibody Pair, B7H3 Matched Antibody Pair, 4Ig-B7-H3 Matched Antibody Pair, B7-H3 Matched Antibody Pair, CD276 molecule Matched Antibody Pair, CD276 molecule S homeolog Matched Antibody Pair, CD276 antigen Matched Antibody Pair, Cd276 molecule Matched Antibody Pair, CD276 Matched Antibody Pair, cd276.S Matched Antibody Pair, cd276 Matched Antibody Pair, Cd276 Matched Antibody Pair
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