PCBP4 Products
(Poly(rC) Binding Protein 4 (PCBP4))
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This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008].
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Featured PCBP4 Categories
PCBP4 Antibodies
High quality antibodies with extensive validation data.
PCBP4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PCBP4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN334457
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN566080
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Guinea Pig, Human, Monkey, Rabbit
Application
WB
Validations
- (1)
Cat. No.
ABIN203088
Quantity
100 μL
Datasheet
Datasheet
Recommended PCBP4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314135
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3085739
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3120546
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PCBP4 products
: "The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer." in: The Journal of biological chemistry, Vol. 292, Issue 32, pp. 13205-13229, (2017) (PubMed).: "Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2." in: The Journal of biological chemistry, Vol. 291, Issue 33, pp. 17303-18, (2016) (PubMed).
: "Alpha CP-4, encoded by a putative tumor suppressor gene at 3p21, but not its alternative splice variant alpha CP-4a, is underexpressed in lung cancer." in: Cancer research, Vol. 64, Issue 12, pp. 4171-9, (2004) (PubMed).
: "The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms." in: RNA (New York, N.Y.), Vol. 8, Issue 3, pp. 265-78, (2002) (PubMed).
: "MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M." in: Molecular and cellular biology, Vol. 20, Issue 15, pp. 5602-18, (2000) (PubMed).
Synonyms and alternative names related to PCBP4
poly(rC) binding protein 4 (pcbp4), poly(rC) binding protein 4 (PCBP4), poly(rC) binding protein 4 (Pcbp4), 1200003L19Rik, AlphaCP-4, CBP, LIP4, MCG10, Pcbp4, PCBP4, wu:fc68f03, zgc:77347Protein level used designations for PCBP4
- poly(rC) binding protein 4
- poly(rC)-binding protein 4
- poly(rC)-binding protein 4-like
- LYST-interacting protein
- RNA binding protein MCG10
- alpha-CP4
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