PCM1 Products
(Pericentriolar Material 1 (PCM1))
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The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. [provided by RefSeq, Sep 2010].
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Featured PCM1 Categories
PCM1 Antibodies
High quality antibodies with extensive validation data.
PCM1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PCM1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PCM1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IF, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN391696
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN391695
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7162885
Quantity
100 μL
Datasheet
Datasheet
Recommended PCM1 ELISA Kits
Recommended PCM1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314322
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422808
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418656
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PCM1 products
: "Mosaic-variegated aneuploidy syndrome mutation or haploinsufficiency in Cep57 impairs tumor suppression." in: The Journal of clinical investigation, Vol. 128, Issue 8, pp. 3517-3534, (2018) (PubMed).: "RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity." in: The EMBO journal, Vol. 34, Issue 1, pp. 97-114, (2015) (PubMed).
: "Cardiac Myocyte De Novo DNA Methyltransferases 3a/3b Are Dispensable for Cardiac Function and Remodeling after Chronic Pressure Overload in Mice." in: PLoS ONE, Vol. 10, Issue 6, pp. e0131019, (2015) (PubMed).
: "Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. ..." in: Nature, Vol. 525, Issue 7570, pp. 479-85, (2015) (PubMed).
: "Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion." in: Journal of cell science, Vol. 127, Issue Pt 8, pp. 1631-9, (2014) (PubMed).
: "Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease." in: Nature communications, Vol. 5, pp. 5288, (2014) (PubMed).
: "A synthetic peptide corresponding to a region of the human pericentriolar material 1 (PCM-1) protein binds β-amyloid (Aβ1-42 ) oligomers." in: Journal of neurochemistry, Vol. 126, Issue 3, pp. 415-24, (2013) (PubMed).
: "BBS mutations modify phenotypic expression of CEP290-related ciliopathies." in: Human molecular genetics, Vol. 23, Issue 1, pp. 40-51, (2013) (PubMed).
: "ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 48, pp. 19691-6, (2012) (PubMed).
: "Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics." in: Molecular bioSystems, Vol. 7, Issue 12, pp. 3223-33, (2011) (PubMed).
Synonyms and alternative names related to PCM1
pericentriolar material 1 (pcm1), pericentriolar material 1 (PCM1), pericentriolar material 1 (Pcm1), pericentriolar material 1 L homeolog (pcm1.L), 2600002H09Rik, 9430077F19Rik, C030044G17Rik, pcm-1, PCM-1, PCM1, ptc4, PTC4, wu:fb30g01, wu:fb94e03, wu:fe14f07Protein level used designations for PCM1
- pericentriolar material 1
- pericentriolar material 1 protein-like
- Pericentriolar material 1 protein-like
- PCM-1
- hPCM-1
- pericentriolar material 1 protein
- pericentriolar material 1, PCM1
- mPCM-1
- pericentriolar material gene 1
- pericentriolar material-1
- xPCM-1
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