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PCSK2 Products

(Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Categories

This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

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Featured PCSK2 Categories

PCSK2 Antibodies

High quality antibodies with extensive validation data.

PCSK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

PCSK2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PCSK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application FACS, IF, IHC, ELISA, WB
Validations
  • (6)
Cat. No. ABIN3032332
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3032333
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7161261
Quantity 100 μg
Datasheet Datasheet

Recommended PCSK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958851
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884115
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384861
Quantity 96 tests
Datasheet Datasheet

Recommended PCSK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3084560
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133304
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314352
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PCSK2 products

van Rijn, Pouwer, Tryfonidou, Grinwis, van der Bend, Beukers, Vastenhout, Drouin, Penning, Meij: "Expression and clinical relevance of paired box protein 7 and sex determining region Y-box 2 in canine corticotroph pituitary adenomas." in: Veterinary journal (London, England : 1997), Vol. 204, Issue 3, pp. 315-21, (2015) (PubMed).

Discher, Bishopric, Wu, Peterson, Webster: "Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element." in: The Journal of biological chemistry, Vol. 273, Issue 40, pp. 26087-93, (1998) (PubMed).

Feo, Antona, Barbieri, Passantino, Calì, Giallongo: "Transcription of the human beta enolase gene (ENO-3) is regulated by an intronic muscle-specific enhancer that binds myocyte-specific enhancer factor 2 proteins and ubiquitous G-rich-box binding factors." in: Molecular and cellular biology, Vol. 15, Issue 11, pp. 5991-6002, (1995) (PubMed).

Giallongo, Venturella, Oliva, Barbieri, Rubino, Feo: "Structural features of the human gene for muscle-specific enolase. Differential splicing in the 5'-untranslated sequence generates two forms of mRNA." in: European journal of biochemistry / FEBS, Vol. 214, Issue 2, pp. 367-74, (1993) (PubMed).

Synonyms and alternative names related to PCSK2

proprotein convertase subtilisin/kexin type 2 (PCSK2), proprotein convertase subtilisin/kexin type 2 (pcsk2), proprotein convertase subtilisin/kexin type 2 (Pcsk2), proprotein convertase subtilisin/kexin type 2 L homeolog (pcsk2.L), 6330411F23Rik, AI839700, NEC-2, Nec-2, NEC 2, NEC2, Nec2, nec2, PC2, pc2, PCSK2, pcsk2, pcsk2-A, Phpp-2, SPC2, spc2

Protein level used designations for PCSK2

  • KEX2-like endoprotease 2
  • neuroendocrine convertase 2
  • prohormone convertase 2
  • NEC 2
  • PC2
  • proprotein convertase 2
  • proprotein convertase subtilisin/kexin type 2
  • proprotein convertase type 2
  • convertase PC2
  • proprotein convertase subtilisin/kexin type 2 L homeolog
  • prohormone convertase2
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