PDE1C Products
(phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
Categories
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009].
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Featured PDE1C Categories
PDE1C Antibodies
High quality antibodies with extensive validation data.
PDE1C ELISA Kits
Reliable ELISA kits for a wide range of species.
PDE1C Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PDE1C Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7146420
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6243943
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6741846
Quantity
100 μL
Datasheet
Datasheet
Recommended PDE1C ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969260
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969259
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958530
Quantity
96 tests
Datasheet
Datasheet
Recommended PDE1C Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3085620
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3123289
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
Cat. No.
ABIN7197331
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PDE1C products
: "Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome." in: Oncotarget, Vol. 8, Issue 8, pp. 13223-13239, (2017) (PubMed).: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." in: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).
: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." in: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).
: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).
: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).
: "Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 297, Issue 5, pp. R1469-76, (2009) (PubMed).
: "Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells." in: Biochemical pharmacology, Vol. 79, Issue 3, pp. 321-9, (2009) (PubMed).
: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase during ontogenesis of chick retina." in: Journal of neuroscience research, Vol. 86, Issue 5, pp. 1017-23, (2008) (PubMed).
: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).
Synonyms and alternative names related to PDE1C
Phosphodiesterase 1c (Pde1c), phosphodiesterase 1C (PDE1C), calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (LOC724389), calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (LOC100019026), phosphodiesterase 1C, calmodulin-dependent b (pde1cb), phosphodiesterase 1C (Pde1c), CG14940, CG14942, CG14943, CG14944, CG31757, CG31758, CG42325, CG44007, Dmel\\CG44007, Dmel_CG14940, Dmel_CG14943, Dmel_CG14944, Dmel_CG31757, Dmel_CG31758, Dmel_CG42325, GB13690, Hcam3, PDE1C, PDE1cProtein level used designations for PDE1C
- CG44007-PB
- CG44007-PC
- CG44007-PD
- CG44007-PE
- CG44007-PG
- CG44007-PH
- CG44007-PJ
- CG44007-PK
- Pde1c-PB
- Pde1c-PC
- Pde1c-PD
- Pde1c-PE
- Pde1c-PG
- Pde1c-PH
- Pde1c-PJ
- Pde1c-PK
- phosphodiesterase 1c
- phosphodiesterase 1C, calmodulin-dependent 70kDa
- calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
- calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C-like
- cam-PDE 1C
- cyclic nucleotide phosphodiesterase 1 C
- phosphodiesterase 1C calmodulin-dependent (70kD)
- Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A)
- hCam-3
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