anti-Guinea Pig Carboxypeptidase E antibody for Western Blotting

Recommended Carboxypeptidase E Antibody (supplied by: Log in to see )

Antigen
Carboxypeptidase E (CPE) Antibodies
  • CPE
  • CPH
  • Cph-1
  • Cph1
  • R74677
  • fat
  • CARBE
  • Cph
  • si:ch211-198g9.2
  • zgc:85981
  • carboxypeptidase E
  • carboxypeptidase E L homeolog
  • CPE
  • cpe
  • Cpe
  • cpe.L
Epitope
N-Term
14
8
5
5
5
5
4
4
3
3
3
3
3
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Guinea Pig, Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
103
60
53
8
8
1
1
1
1
1
1
Host
Rabbit
97
4
3
Clonality
Polyclonal
Conjugate
Un-conjugated
5
4
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
81
41
29
23
14
13
10
9
8
7
5
1
1
1
1
Options
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Catalog No. ABIN2787685
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN958305 IHC IHC (p) WB Rabbit IgG AA 36-85 Log in to see Polyclonal 0

General

Antigen Carboxypeptidase E (CPE) Antibodies
Epitope N-Term
(14), (8), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Guinea Pig, Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
(103), (60), (53), (8), (8), (1), (1), (1), (1), (1), (1)
Host Rabbit
(97), (4), (3)
Clonality
Polyclonal
Conjugate Un-conjugated
(5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(81), (41), (29), (23), (14), (13), (10), (9), (8), (7), (5), (1), (1), (1), (1)
Pubmed 1 reference available
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Product details

Target Details Application Details Handling References Images
Blocking Peptide Blocking peptide for this product available: ABIN975234
Sequence GMRRRRRLQQ EDGISFEYHR YPELREALVS VWLQCTAISR IYTVGRSFEG
Predicted Reactivity Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
Characteristics This is a rabbit polyclonal antibody against CPE. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CPE

Target Details

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Antigen
Alternative Name CPE (CPE Antibody Abstract)
Background CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteinsThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: PRKAA1, UBC, LRIF1, POLDIP2, MED31, ROBO2, POLA2, CHD3, TRH, NTS, GTF3C1, UTP14A, RPA1, PMCH, INS, GCG, GAST, CCK, BDNF,
Protein Size: 476
Molecular Weight 52 kDa
Gene ID 1363
NCBI Accession NM_001873, NP_001864
UniProt P16870
Pathways Peptide Hormone Metabolism, Synaptic Membrane

Application Details

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Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 476 AA

Restrictions For Research Use only

Handling

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Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

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Background publications

Wang, Zhang, Yang, Zhu, Wang, Chen, Cao, Huang, Ma, Jia: "Association of human carboxypeptidase E exon5 gene polymorphisms with angiographical characteristics of coronary atherosclerosis in a Chinese population." in: Acta pharmacologica Sinica, Vol. 29, Issue 6, pp. 736-44, 2008

Images

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Supplier Images
Western Blotting (WB) image for anti-Carboxypeptidase E (CPE) (N-Term) antibody (ABIN2787685) WB Suggested Anti-CPE Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1...
Immunohistochemistry (IHC) image for anti-Carboxypeptidase E (CPE) (N-Term) antibody (ABIN2787685) Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5µ...