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Mouse (Murine) FSHB ELISA Kit for Sandwich ELISA - ABIN455141
Hejmej, Kotula-Balak, Chojnacka, Kuras, Lydka-Zarzycka, Bilinska: Photoperiod-Dependent Effects of 4-tert-Octylphenol on Adherens and Gap Junction Proteins in Bank Vole Seminiferous Tubules. in International journal of endocrinology 2013
Action of Lh and Fsh (show BRD2 ELISA Kits) signaling is redundant in that either alone can support zebrafish spermatogenesis.
FSH (show BRD2 ELISA Kits)-deficient zebrafish (fshb(-/-)) were surprisingly fertile in both sexes; however, the development of both the ovary and testis was significantly delayed.
zfFSHbeta promoter responded to 6h of gonadotropin-releasing hormone treatment by activating calcium influx and protein kinase C (PKC (show PKC ELISA Kits)), but after 24h, GnRH (show GNRH1 ELISA Kits) induction was generated by activation of extracellular-regulated kinase 1/2 and repression by PKC (show PKC ELISA Kits).
LHbeta (show LHB ELISA Kits) and LH-R (show LHCGR ELISA Kits) mRNA expression might be involved in initial maturation events of gametes, at least in males, while the gradually increase of FSH-R (show FSHR ELISA Kits) mRNA coincided with the advancing process of gamete maturation in both sexes
A major regulatory mechanism for FSH (show BRD2 ELISA Kits) glycosylation involves control of beta-subunit (show POLG ELISA Kits) N-glycosylation, possibly by inhibition of oligosaccharyl transferase. Two primate species exhibited the same all-or-none pattern of pituitary FSHbeta glycosylation.
the in vivo bioactivities of FSH (show BRD2 ELISA Kits) glycoforms in Fshb null mice using a pharmacological rescue approach, was investigated.
These mice showed an increase in FSH (show BRD2 ELISA Kits) levels, but they remained in a prepubertal state. Together with previous findings, our data indicate that leptin (show LEP ELISA Kits)-selective action in gonadotropes serves a role in adult reproductive physiology but is not sufficient to allow pubertal maturation in mice.
GnRH (show GNRH1 ELISA Kits) stimulated the secretion of the VGF (show VGF ELISA Kits)-derived peptide NERP1 (show VGF ELISA Kits). NERP1 (show VGF ELISA Kits) caused a concentration-dependent decrease in Fshb gene induction.
the signaling pathways mediating GnRH activation of CREB and ICER are distinct, contributing to the decoding of the pulsatile GnRH to regulate FSHbeta expression.
Data show that estradiol or bisphenol A decreased expression of luteinizing hormone beta (Lhb (show LHB ELISA Kits)), follicle stimulating hormone beta (Fshb), and intracellular adhesion molecule (show NCAM1 ELISA Kits)-5 (Icam5 (show ICAM5 ELISA Kits)) in females but only decreased expression of Icam5 (show ICAM5 ELISA Kits) in males.
GnRH (show GNRH1 ELISA Kits) stimulation of Fshb expression is dependent on miR (show MLXIP ELISA Kits)-132/212 and involves a SIRT1 (show SIRT1 ELISA Kits)-FOXO1 (show FOXO1 ELISA Kits) pathway.
results suggest that FOXO1 (show FOXO1 ELISA Kits) binding to the proximal Fshb promoter as well as FOXO1 (show FOXO1 ELISA Kits) interaction with SMAD3 (show SMAD3 ELISA Kits)/4 proteins may result in decreased activin (show Actbeta ELISA Kits) induction of Fshb in gonadotropes
SCGB3A2 (show SCGB3A2 ELISA Kits) regulates FSH (show BRD2 ELISA Kits)/LH production in the anterior pituitary lobe.
Data suggest that the BMP2 (show BMP2 ELISA Kits)-like Activin A (show INHBA ELISA Kits)/BMP2 (show BMP2 ELISA Kits) chimera AB215 regulates follicle stimulating hormone beta (FSHbeta) induction in LbetaT2 gonadotroph cells due to its ability to block activin A (show INHBA ELISA Kits) signaling.
Two regions of the proximal Fshb promoter (-50/-41 and -30/-21) appear to be necessary for FOXO1 (show FOXO1 ELISA Kits) suppression of GnRH (show GNRH1 ELISA Kits)-induced Fshb transcription.
Genetic variation affecting FSH (show BRD2 ELISA Kits) production (FSHB c.-211G>T) was associated with age at pubertal onset, as assessed by testicular enlargement. The effect appeared further modified by coexistence of genetic variation affecting FSH (show BRD2 ELISA Kits) sensitivity (FSHR (show FSHR ELISA Kits) c.-29G>A).
A novel homozygous mutation in the FSHbeta gene (c.343C > T) identified in a male patient with isolated FSH (show BRD2 ELISA Kits) deficiency and infertility.
Association of the FSHB 211G > T polymorphism with male infertility in Han-Chinese
Genetic variations of FSH (show BRD2 ELISA Kits) signaling appear to determine the individual set point of the hypothalamic-pituitary-gonadal axis already early in life.
Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb gene sensitivity to gonadotropin-releasing hormone pulse frequency
Variants in FSHB gene are associated with polycystic ovary syndrome and LH levels in Han Chinese women.
Data indicate that compared with normal eggs, oocytes with a brown zona pellucida (ZP) were found to have a higher ZP thickness (ZPT), lower embryo quality and lower pregnancy rate, which might be due to a high gonadotropin (Gn) dosage injection and high serum follicle stimulating hormone (FSH (show BRD2 ELISA Kits)) levels.
genetic association studies in peripubertal girls in Denmark: Data suggest that an SNP in FSHR (follicle stimulating hormone receptor (show FSHR ELISA Kits), c.2039A>G) is associated with blood levels of FSH (show BRD2 ELISA Kits), LH, and estradiol; minor alleles in FSHB (follicle stimulating hormone beta subunit, c.-211G>T) and FSHR (show FSHR ELISA Kits) (c.-29G>A) are associated with delayed pubertal onset.
The FSHB -211G>T variant attenuates serum FSH (show BRD2 ELISA Kits) levels in the supraphysiological gonadotropin setting of Klinefelter syndrome
Study describes generation and characterization of a new Fshb-iCre deleter strain using 4.7 kb of ovine Fshb promoter sequences driving iCre expression exclusively in the gonadotrope lineage with mice developing normally, and fertile.
the novel cis (show CISH ELISA Kits)-regulatory element generated by the c.-1539_-1538delGGinsTTAACT mutations might play an important role in repressing FSHB transcription, possibly leading to reduced fertility
A 200-base region in the bovine FSHbeta 3' untranslated region downregulates reporter expression at the translational level via interactions between AREs in both the 3'UTR (show UTS2R ELISA Kits) and transfactors.
The shift in FSH (show BRD2 ELISA Kits) isoforms toward a greater abundance of the less acidic isoforms appears to be a key component in determining the capability for producing a preovulatory rise in estradiol.
The effect of a single nucleotide polymorphism of the follicle stimulating hormone beta chain on bull fertility and semen quality is reported.
As in vitro experiments in the present study suggested that LHX2 (show LHX2 ELISA Kits) regulated the expression of Fshbeta, it is possible that LHX2 (show LHX2 ELISA Kits) controls FSH (show BRD2 ELISA Kits) synthesis at the transcriptional level.
Results showed that the effects of FSHb, ESR (show ESR1 ELISA Kits), and PRLR (show PRLR ELISA Kits) genes were significant in the Tibet pig population, and the effective genotypes of the three genes for reproductive traits were BB, BB, and AA, respectively.
LHX3 (show LHX3 ELISA Kits) LIM homeodomain (show LHX2 ELISA Kits) transcription factor is involved in activation of the FSH beta-subunit (show POLG ELISA Kits) gene in the pituitary gonadotrope cell.
Prop-1 (show PROP1 ELISA Kits) participates in the regulation of FSHbeta gene
A allele of FSHbeta-1 locus in all the population and FSHbeta-2 locus in pigs of the first parity had the positive effective on TNB, NBA, and WB.
The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein.
, Gth I
, follicle-stimulating hormone beta subunit
, follitropin subunit beta
, FSH beta
, follcle-stimulating hormone beta subunit
, follicle stimulating hormone, beta polypeptide
, follitropin beta chain
, Follicle-stimulating hormone beta subunit
, follicle stimulating hormone beta-subunit
, follitropin, beta chain
, follicle - stimulating hormone subunit beta
, follicle stimulating hormone beta
, follicle-stimulating hormone beta-subunit
, follicle-stimulating hormone subunit beta
, class 1 follicle-stimulating hormone beta polypeptide
, class 2 follicle-stimulating hormone beta polypeptide
, follicule stimulating hormone, beta polypeptide
, follicle stimulating hormone beta subunit
, follitropin beta subunit