Diencephalon/mesencephalon Homeobox 1 (DMBX1) (C-Term) Peptide
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- Target See all DMBX1 products
- DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))
- Protein Region
- C-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SLSAAAAAHQ GVWGSPLLPA PPTGLAPASA ALNSKTTSIE NLRLRAKQHA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Dmbx1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))
- Synonyms
- MBX Peptide, OTX3 Peptide, PAXB Peptide, DMBX1 Peptide, Atx Peptide, Cdmx Peptide, Mbx Peptide, Otx3 Peptide, mbx2 Peptide, zgc:112395 Peptide, dmbx1 Peptide, mbx Peptide, otx3 Peptide, pox1 Peptide, zMbx1 Peptide, diencephalon/mesencephalon homeobox 1 Peptide, diencephalon/mesencephalon homeobox 1b Peptide, diencephalon/mesencephalon homeobox 1a Peptide, DMBX1 Peptide, Dmbx1 Peptide, dmbx1b Peptide, dmbx1a Peptide
- Background
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Dmbx1 functions as a transcriptional repressor. It may repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence and is required for brain development, neonatal survival, postnatal growth, and nursing ability.
Alias Symbols: Atx, Cdmx, Mbx, Otx3
Protein Size: 381 - Molecular Weight
- 41 kDa
- Gene ID
- 140477
- NCBI Accession
- NM_130865, NP_570935
- UniProt
- Q91ZK4
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