Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2) (N-Term) Peptide
GGA2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GGA2 products
- GGA2 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MLKKQGIIKQ DPKLPVDKIL PPPSPWPKSS IFDADEEKSK LLTRLLKSNH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GGA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GGA2 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2))
- Synonyms
- 1200007E24Rik Peptide, mKIAA1080 Peptide, VEAR Peptide, golgi associated, gamma adaptin ear containing, ARF binding protein 2 Peptide, Gga2 Peptide, GGA2 Peptide
- Background
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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
Alias Symbols: VEAR
Protein Size: 613 - Molecular Weight
- 67 kDa
- Gene ID
- 23062
- NCBI Accession
- NM_015044, NP_055859
- UniProt
- Q9UJY4
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