FYVE and Coiled-Coil Domain Containing 1 (FYCO1) (N-Term) Peptide
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- Target See all FYCO1 products
- FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PLAQELEATR DSLDKKNQHL ASFPGWLAMA QQKADTASDT KGRQEPIPSD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FYCO1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))
- Synonyms
- FCYO1 Peptide, FYCO1 Peptide, CATC2 Peptide, CTRCT18 Peptide, RUFY3 Peptide, ZFYVE7 Peptide, 2810409M01Rik Peptide, Mem2 Peptide, FYVE and coiled-coil domain containing 1 Peptide, si:dkey-246j7.1 Peptide, FYCO1 Peptide, si:dkey-246j7.1 Peptide, Fyco1 Peptide
- Background
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This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).
Alias Symbols: DKFZp779K1152, FLJ13335, MGC126517, MGC126519, RUFY3, ZFYVE7
Protein Size: 1478 - Molecular Weight
- 167 kDa
- Gene ID
- 79443
- NCBI Accession
- NM_024513, NP_078789
- UniProt
- Q9BQS8
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