Platelet-Derived Growth Factor Receptor-Like (PDGFRL) (N-Term) Peptide
PDGFRL
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PDGFRL products
- PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KVKPKIPKMK DRDSANSAPK TQSIMMQVLD KGRFQKPAAT LSLLAGQTVE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PDGFRL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))
- Synonyms
- zgc:56104 Peptide, zgc:77677 Peptide, MGC82397 Peptide, PDGFRL Peptide, pdgrl Peptide, prlts Peptide, MGC107901 Peptide, PDGRL Peptide, PRLTS Peptide, 1110039P19Rik Peptide, AV013190 Peptide, platelet-derived growth factor receptor-like Peptide, platelet derived growth factor receptor like L homeolog Peptide, platelet derived growth factor receptor like Peptide, pdgfrl Peptide, pdgfrl.L Peptide, PDGFRL Peptide, Pdgfrl Peptide
- Background
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This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
Alias Symbols: PDGRL, PRLTS
Protein Size: 375 - Molecular Weight
- 38 kDa
- Gene ID
- 5157
- NCBI Accession
- NM_006207, NP_006198
- UniProt
- Q15198
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