Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3) (Middle Region) Peptide
EIF2B3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EIF2B3 products
- EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ENGSITSIRS ELIPYLVRKQ FSSASSQQGQ EEKEEDLKKK ELKSLDIYSF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EIF2B3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))
- Synonyms
- zgc:56473 Peptide, 1190002P15Rik Peptide, EIF-2B Peptide, EIF2Bgamma Peptide, eukaryotic translation initiation factor 2B subunit gamma L homeolog Peptide, eukaryotic translation initiation factor 2B, subunit 3 gamma Peptide, eukaryotic translation initiation factor 2B subunit gamma Peptide, eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa Peptide, eukaryotic translation initiation factor 2B, subunit 3 Peptide, eif2b3.L Peptide, eif2b3 Peptide, EIF2B3 Peptide, Eif2b3 Peptide
- Background
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The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EIF-2B, EIF2Bgamma
Protein Size: 452 - Molecular Weight
- 50 kDa
- Gene ID
- 8891
- NCBI Accession
- NM_020365, NP_065098
- UniProt
- Q9NR50
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