rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (Middle Region) Peptide
ROCK2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all ROCK2 products
- ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KNAEYQRKAD HEADKKRNLE NDVNSLKDQL EDLKKRNQNS QISTEKVNQL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ROCK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
- Synonyms
- rocka-a Peptide, xROK Peptide, rock2 Peptide, rok2 Peptide, ROCK2 Peptide, B230113H15Rik Peptide, ROKalpha Peptide, Rho-kinase Peptide, Rock-II Peptide, Rock2m Peptide, mKIAA0619 Peptide, ROCK-II Peptide, ROK Peptide, Rho-associated, coiled-coil containing protein kinase 2 L homeolog Peptide, rho-associated, coiled-coil containing protein kinase 2a Peptide, Rho associated coiled-coil containing protein kinase 2 Peptide, Rho-associated, coiled-coil containing protein kinase 2 Peptide, Rho-associated coiled-coil containing protein kinase 2 Peptide, rock2.L Peptide, rock2a Peptide, ROCK2 Peptide, Rock2 Peptide
- Background
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The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
Alias Symbols: KIAA0619, ROCK-II
Protein Interaction Partner: MBP,MAGEC1,PPP1R12A,STAU1,IKBKE,RHOA,STK16
Protein Size: 1388 - Molecular Weight
- 153 kDa
- Gene ID
- 9475
- NCBI Accession
- NM_004850, NP_004841
- UniProt
- O75116
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