SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1) Peptide
SMARCE1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all SMARCE1 products
- SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMARCE1 antibody (Catalog #: ARP38224_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
- Synonyms
- BAF57 Peptide, XBaf57 Peptide, MGC52696 Peptide, MGC69429 Peptide, MGC81726 Peptide, SMARCE1 Peptide, DKFZp459O2235 Peptide, fb54d11 Peptide, wu:fb33d02 Peptide, wu:fb54d11 Peptide, Baf57 Peptide, 2810417B20Rik Peptide, 5830412H02Rik Peptide, 9030408N19Rik Peptide, Baf27 Peptide, RGD1304726 Peptide, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 Peptide, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 L homeolog Peptide, smarce1 Peptide, SMARCE1 Peptide, smarce1.L Peptide, Smarce1 Peptide
- Background
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SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
Alias Symbols: BAF57
Protein Interaction Partner: DISC1,tax,ARID2,BAZ1B,BRMS1,ESR1,ESR2,NCOA1,NCOA2,NCOA3,NR3C1,RCOR1,RELB,SMAD1,SMARCA4,SRC,ACTB,ACTL6A,ARID1A,BAZ1B,ESR1,ESR2,Esr1,GATA1,KLF1,MECP2,NCOA1,NR3C1,RELB,SMARCA2,SMARCA4,SMARCB1,SMARCC1,SMARCC2,STAT2,TFE3
Protein Size: 411 - Molecular Weight
- 47 kDa
- Gene ID
- 6605
- NCBI Accession
- NM_003079, NP_003070
- UniProt
- Q969G3
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