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Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9) (C-Term) Peptide

OS9 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2182262
  • Target See all OS9 products
    OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))
    Protein Region
    C-Term
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    LKEIFFNILV PGAEEAQKER QRQKELESNY RRVWGSPGGE GTGDLDEFDF
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-OS9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))
    Synonyms
    OS-9 Peptide, zgc:153838 Peptide, 4632413K17Rik Peptide, AU022351 Peptide, Os-9 Peptide, ERLEC2 Peptide, OS9, endoplasmic reticulum lectin Peptide, osteosarcoma amplified 9, endoplasmic reticulum lectin Peptide, amplified in osteosarcoma Peptide, OS9 Peptide, os9 Peptide, Os9 Peptide
    Background
    This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: ERLEC2, OS-9

    Protein Size: 667
    Molecular Weight
    73 kDa
    Gene ID
    10956
    NCBI Accession
    NM_006812, NP_006803
    UniProt
    Q13438
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