Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9) (C-Term) Peptide
OS9
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all OS9 products
- OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))
- Protein Region
- C-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LKEIFFNILV PGAEEAQKER QRQKELESNY RRVWGSPGGE GTGDLDEFDF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-OS9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))
- Synonyms
- OS-9 Peptide, zgc:153838 Peptide, 4632413K17Rik Peptide, AU022351 Peptide, Os-9 Peptide, ERLEC2 Peptide, OS9, endoplasmic reticulum lectin Peptide, osteosarcoma amplified 9, endoplasmic reticulum lectin Peptide, amplified in osteosarcoma Peptide, OS9 Peptide, os9 Peptide, Os9 Peptide
- Background
-
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: ERLEC2, OS-9
Protein Size: 667 - Molecular Weight
- 73 kDa
- Gene ID
- 10956
- NCBI Accession
- NM_006812, NP_006803
- UniProt
- Q13438
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