Thioredoxin (TXN) (C-Term) Peptide
TXN
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TXN products
- TXN (Thioredoxin (TXN))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TXN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TXN (Thioredoxin (TXN))
- Synonyms
- TRDX Peptide, TRX Peptide, TRX1 Peptide, ADF Peptide, AW550880 Peptide, Trx1 Peptide, Txn Peptide, trx Peptide, TXN Peptide, SCM1.18 Peptide, trxA3 Peptide, thioredoxin Peptide, TR-1 Peptide, Trx-1 Peptide, thioredoxin Peptide, thioredoxin 1 Peptide, thioredoxin L homeolog Peptide, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) Peptide, thioredoxin pseudogene Peptide, cytosolic thioredoxin Trx1 Peptide, TXN Peptide, Txn1 Peptide, txn.L Peptide, txn Peptide, trx Peptide, SCO0885 Peptide, PHG25ORF099c Peptide, LOC100349046 Peptide, Txn Peptide, trx1 Peptide
- Background
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TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. It nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. It induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55)
Alias Symbols: TRDX, TRX, TRX1
Protein Size: 105 - Molecular Weight
- 11 kDa
- Gene ID
- 7295
- NCBI Accession
- NM_003329, NP_003320
- UniProt
- P10599
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