Sin3A-Associated Protein, 18kDa (SAP18) (N-Term) Peptide
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- Target See all SAP18 products
- SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ESRVTQEEIK KEPEKPIDRE KTCPLLLRVF TTNNGRHHRM DEFSRGNVPS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SAP18 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))
- Synonyms
- zgc:73118 Peptide, C530046K05Rik Peptide, D11Ertd539e Peptide, EMegR4 Peptide, Sinbp1 Peptide, 2HOR0202 Peptide, SAP18P Peptide, Sin3A-associated protein Peptide, Sin3-associated polypeptide 18 Peptide, Sin3A associated protein 18 Peptide, Sin3A associated protein 18kDa S homeolog Peptide, sap18 Peptide, Sap18 Peptide, sap18.S Peptide, SAP18 Peptide
- Background
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Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.
Alias Symbols: 2HOR0202, SAP18P
Protein Size: 153 - Molecular Weight
- 16 kDa
- Gene ID
- 10284
- NCBI Accession
- NM_005870, NP_005861
- UniProt
- O00422
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