Chromosome 21 Open Reading Frame 2 (C21orf2) (C-Term) Peptide
C21orf2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all C21orf2 products
- C21orf2 (Chromosome 21 Open Reading Frame 2 (C21orf2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DPLDSEEEAT SGAQDERGLK PPSRGQFPSL SARDASSSHR GRNVLTAILL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-C21orf2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- C21orf2 (Chromosome 21 Open Reading Frame 2 (C21orf2))
- Synonyms
- MGC75902 Peptide, YF5/A2 Peptide, chromosome 21 open reading frame 2 S homeolog Peptide, chromosome 21 open reading frame 2 Peptide, chromosome 9 C21orf2 homolog Peptide, c21orf2.S Peptide, c21orf2 Peptide, C9H21orf2 Peptide, C21orf2 Peptide
- Background
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Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.
Alias Symbols: A2, YF5, YF5/A2
Protein Size: 215 - Molecular Weight
- 23 kDa
- Gene ID
- 755
- NCBI Accession
- NM_004928, NP_004919
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