Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (C-Term) Peptide
PPP1CA
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
-
- Target See all PPP1CA products
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
- Protein Region
- C-Term
- Origin
- Human, Mouse
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAD KNKGKYGQFS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Ppp1ca Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
- Synonyms
- PP-1A Peptide, PP1A Peptide, PP1alpha Peptide, PPP1A Peptide, Ppp1c Peptide, dism2 Peptide, ppp1a Peptide, wu:fc04c08 Peptide, wu:fc09b07 Peptide, wu:fc30g11 Peptide, wu:fe05h08 Peptide, zgc:85729 Peptide, Ppp1ca Peptide, fb18b03 Peptide, fd20h04 Peptide, wu:fb18b03 Peptide, wu:fd20h04 Peptide, wu:fl22a03 Peptide, zgc:55744 Peptide, zgc:76940 Peptide, protein phosphatase 1 catalytic subunit alpha Peptide, protein phosphatase 1, catalytic subunit, alpha isoform Peptide, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog Peptide, protein phosphatase 1, catalytic subunit, alpha isozyme Peptide, protein phosphatase 1, catalytic subunit, alpha isozyme a Peptide, protein phosphatase 1, catalytic subunit, alpha isozyme b Peptide, PPP1CA Peptide, Ppp1ca Peptide, ppp1ca.L Peptide, ppp1ca Peptide, ppp1caa Peptide, ppp1cab Peptide
- Background
-
Ppp1ca is a protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Regulates NEK2 function in terms of kinase activity and centrosome number and splitting, both in the presence and absence of radiation-induced DNA damage. Regulator of neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development.
Alias Symbols: Ppp1c, dism2
Protein Size: 330 - Molecular Weight
- 37 kDa
- Gene ID
- 19045
- NCBI Accession
- NM_031868, NP_114074
- UniProt
- P62137
-
You are here:
