Prostaglandin E Synthase 2 (PTGES2) (N-Term) Peptide
PTGES2
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all PTGES2 products
- PTGES2 (Prostaglandin E Synthase 2 (PTGES2))
- Protein Region
- N-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RLLGAAALAL GGALGLYHTV RWHQRSQDLR AERSAAQLPL SNSLQLTLYQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Ptges2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PTGES2 (Prostaglandin E Synthase 2 (PTGES2))
- Synonyms
- C9orf15 Peptide, GBF-1 Peptide, GBF1 Peptide, PGES2 Peptide, mPGES-2 Peptide, Pges Peptide, 2410099E23Rik Peptide, D2Ertd369e Peptide, mPGES Peptide, mPGES-1 Peptide, PTGES2 Peptide, ptges2 Peptide, zgc:56527 Peptide, gbf1 Peptide, pges2 Peptide, 0610038H10Rik Peptide, C79137 Peptide, Gbf1 Peptide, Mpges2 Peptide, Pges2 Peptide, MPGES-2 Peptide, prostaglandin E synthase 2 Peptide, prostaglandin E synthase Peptide, prostaglandin E synthase 2-like Peptide, PTGES2 Peptide, Ptges Peptide, Ptges2 Peptide, ptgesl Peptide, CpipJ_CPIJ003988 Peptide, CpipJ_CPIJ018524 Peptide, ptges2 Peptide
- Background
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The protein encoded by this gene is a Golgi membrane-associated prostaglandin E synthase candidate, which is capable of catalyzing the conversion of prostaglandin H2 to prostaglandin E2 in vitro. However, a study using mice deficient of this gene suggests that this enzyme does not contribute to prostaglandin E2 biosynthesis in vivo. This protein is synthesized as a Golgi membrane-bound protein, but its N-terminal hydrophobic region is cleaved off during protein maturation to produce the predominant soluble truncated form that still retains the enzyme activity. This soluble protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE), possibly via an interaction with CAAAT/enhancer-binding protein-beta.
Alias Symbols: 0610038H10Rik, C79137, Gbf1, Mpges2, Pges2
Protein Size: 384 - Molecular Weight
- 43 kDa
- Gene ID
- 96979
- NCBI Accession
- NM_133783, NP_598544
- UniProt
- Q8BWM0
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