Par-6 Partitioning Defective 6 Homolog beta (PARD6B) (N-Term) Peptide
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- Target See all PARD6B products
- PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))
- Protein Region
- N-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SKFGAEFRRF SLERSKPGKF EEFYGLLQHV HKIPNVDVLV GYADIHGDLL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Pard6b Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))
- Synonyms
- PARD6B Peptide, AV025615 Peptide, Par6b Peptide, PAR6B Peptide, par-6 Peptide, par6 Peptide, pard6beta Peptide, si:dkey-192i18.6 Peptide, PAR-6 Peptide, PAR-6B Peptide, par-6 family cell polarity regulator beta Peptide, par-6 family cell polarity regulator beta S homeolog Peptide, par-6 partitioning defective 6 homolog beta (C. elegans) Peptide, PARD6B Peptide, Pard6b Peptide, pard6b.S Peptide, pard6b Peptide
- Background
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Pard6b is a adapter protein involved in asymmetrical cell division and cell polarization processes. It is probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Alias Symbols: AV025615, Par6b
Protein Size: 371 - Molecular Weight
- 40 kDa
- Gene ID
- 58220
- NCBI Accession
- NM_021409, NP_067384
- UniProt
- Q9JK83
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