SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B) (C-Term) Peptide
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- Target See all SLX1A/GIYD2 (SLX1B) products
- SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QEEPGQLLPL EGQCPCCEKS LLWGDLIWLC QMDTEKEVED SELEEAHWTD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SLX1B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))
- Synonyms
- 1110030E23Rik Peptide, 2410170E21Rik Peptide, 4833422P03Rik Peptide, AI853643 Peptide, Giyd1 Peptide, Giyd2 Peptide, LRRGT00058 Peptide, RGD1311568 Peptide, GIYD2 Peptide, SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) Peptide, SLX1 homolog B, structure-specific endonuclease subunit Peptide, Slx1b Peptide, SLX1B Peptide
- Background
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This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication, this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.
Protein Size: 275 - Molecular Weight
- 30 kDa
- Gene ID
- 79008
- UniProt
- Q9BQ83
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