Iduronidase, alpha-L- (IDUA) (C-Term) Peptide
IDUA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IDUA products
- IDUA (Iduronidase, alpha-L- (IDUA))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DPVAAAPRPL PAGGRLTLRP ALRLPSLLLV HVCARPEKPP GQVTRLRALP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IDUA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IDUA (Iduronidase, alpha-L- (IDUA))
- Synonyms
- IDA Peptide, MPS1 Peptide, 6030426D08 Peptide, alpha-L-iduronidase Peptide, MGC80842 Peptide, si:ch211-12e13.9 Peptide, IDUA Peptide, iduronidase, alpha-L- Peptide, iduronidase, alpha-L- L homeolog Peptide, alpha-L-iduronidase Peptide, IDUA Peptide, Idua Peptide, idua.L Peptide, idua Peptide, LOC5564727 Peptide
- Background
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This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).
Protein Size: 675 - Molecular Weight
- 74 kDa
- Gene ID
- 3425
- UniProt
- P35475
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