Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (C-Term) Peptide
UHRF1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UHRF1 products
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DDEPGPWTKE GKDRIKKLGL TMQYPEGYLE ALANREREKE NSKREEEEQQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UHRF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
- Synonyms
- ICBP90 Peptide, Np95 Peptide, RNF106 Peptide, hNP95 Peptide, hUHRF1 Peptide, AL022808 Peptide, NP95 Peptide, fb97f09 Peptide, wu:fb97f09 Peptide, zgc:63539 Peptide, UHRF1 Peptide, ubiquitin like with PHD and ring finger domains 1 Peptide, ubiquitin-like, containing PHD and RING finger domains, 1 Peptide, ubiquitin-like with PHD and ring finger domains 1 Peptide, UHRF1 Peptide, Uhrf1 Peptide, uhrf1 Peptide
- Background
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This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Size: 793 - Molecular Weight
- 90 kDa
- Gene ID
- 29128
- UniProt
- Q96T88
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