Epidermal Growth Factor Receptor (EGFR) (AA 988-993), (pTyr5) Peptide
EGFR
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- Target See all EGFR products
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Protein Region
- pTyr5, AA 988-993
- Purity
- 95 %
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- Restrictions
- For Research Use only
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- Storage
- -20 °C
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- Target
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Synonyms
- C-erb Peptide, CG10079 Peptide, D-EGFR Peptide, D-Egf Peptide, DEGFR Peptide, DER Peptide, DER flb Peptide, DER/EGFR Peptide, DER/faint little ball Peptide, DER/top Peptide, DER/torpedo Peptide, DER1 Peptide, DEgfr Peptide, Degfr Peptide, Der Peptide, DmHD-33 Peptide, Dmel\\CG10079 Peptide, EFG-R Peptide, EGF-R Peptide, EGFR Peptide, EGFr Peptide, EGfr Peptide, EK2-6 Peptide, Egf Peptide, Egf-r Peptide, EgfR Peptide, El Peptide, Elp Peptide, Elp-1 Peptide, Elp-B1 Peptide, Elp-B1RB1 Peptide, HD-33 Peptide, TOP Peptide, Torpedo/DER Peptide, Torpedo/Egfr Peptide, c-erbB Peptide, d-egf-r Peptide, dEGFR Peptide, dEGFR1 Peptide, dEgfr Peptide, der Peptide, egfr Peptide, flb Peptide, l(2)05351 Peptide, l(2)09261 Peptide, l(2)57DEFa Peptide, l(2)57EFa Peptide, l(2)57Ea Peptide, mor1 Peptide, top Peptide, top/DER Peptide, top/flb Peptide, torpedo/Egfr Peptide, torpedo/egfr Peptide, EGFR12 Peptide, EGFR15 Peptide, egfr1 Peptide, Erbb2 Peptide, ERBB Peptide, ERBB1 Peptide, HER1 Peptide, PIG61 Peptide, mENA Peptide, ErbB-1 Peptide, Errp Peptide, 9030024J15Rik Peptide, AI552599 Peptide, Erbb Peptide, Errb1 Peptide, Wa5 Peptide, wa-2 Peptide, wa2 Peptide, epidermal growth factor receptor Peptide, Epidermal growth factor receptor Peptide, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) Peptide, EGFR Peptide, Egfr Peptide, egfra Peptide, egfr1 Peptide, LOC5564544 Peptide
- Background
- This phosphotyrosil peptide sequence is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). Using synthetic pTyr-containing peptides that correspond to natural phosphorylation sites in proteins, several groups have demonstrated that PTPases display a range of kcat/Km values for these relatively short peptide substrates. This peptide is a minimal (6 residues) peptide substrate for both the Yersinia PTPase and the mammalian PTP1. It is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B).
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