Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 1-27) Peptide
ADCYAP1
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- Target See all PACAP (ADCYAP1) products
- PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))
- Protein Region
- AA 1-27
- Purification
- Purified
- Purity
- > 95 %
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Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) peptide
ADCYAP1 Reactivity: Mouse Host: Escherichia coli (E. coli) IP, SDS, WB, ELISA Dithiothreitol (DTT)
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- Restrictions
- For Research Use only
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- Storage
- -20 °C
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- Target
- PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))
- Synonyms
- PACAP Peptide, grf Peptide, Pacap Peptide, adcyap1 Peptide, GRF-PACAP Peptide, zgc:103760 Peptide, xx:af217251 Peptide, pacap Peptide, ADCYAP1 Peptide, PACAP2 Peptide, acap1l Peptide, pacap1b Peptide, wu:fj30e08 Peptide, zgc:101522 Peptide, zgc:92555 Peptide, adenylate cyclase activating polypeptide 1 Peptide, adenylate cyclase activating polypeptide 1a Peptide, adenylate cyclase activating polypeptide 1 (pituitary) Peptide, adenylate cyclase activating polypeptide 1b Peptide, ADCYAP1 Peptide, Adcyap1 Peptide, adcyap1a Peptide, adcyap1 Peptide, adcyap1b Peptide
- Background
- PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats. PACAP (1-27) shows considerable homology with Vasoactive Intestinal Polypeptide (VIP), and can stimulate adenylate cyclase much more potently than VIP. The PACAP(1-27)-induced increase in pancreatic venous blood flow was blocked by PACAP(6-27) but not by atropine. Therefore, the endocrine secretagogue effect of PACAP(1-27) is primarily mediated by the PAC(1) receptor, and that PACAP(1-27) may interact with muscarinic receptor function in PACAP-induced insulin and glucagon secretion in the canine pancreas in vivo.
- CAS-No
- 127317-03-7
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