Myeloid Cell Nuclear Differentiation Antigen (MNDA) (Middle Region) Peptide
MNDA
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all MNDA products
- MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KRKTPNKEKT EAKRNKVSQE QSKPPGPSGA STSAAVDHPP LPQTSSSTPS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MNDA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
- Synonyms
- PYHIN3 Peptide, A730048F03 Peptide, Ifi205b Peptide, myeloid cell nuclear differentiation antigen Peptide, interferon activated gene 211 Peptide, MNDA Peptide, Ifi211 Peptide
- Background
-
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.
Alias Symbols: PYHIN3
Protein Size: 407 - Gene ID
- 4332
- NCBI Accession
- NM_002432, NP_002423
- UniProt
- P41218
-
You are here:
