Protein Regulator of Cytokinesis 1 (PRC1) (Middle Region) Peptide
PRC1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PRC1 products
- PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
- Protein Region
- Middle Region
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LWEQEHSKAF MVNGQKFMEY VAEQWEMHRL EKERAKQERQ LKNKKQTETE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PRC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
- Synonyms
- cb212 Peptide, prc1 Peptide, prc1l Peptide, zgc:55982 Peptide, zgc:86918 Peptide, MGC68845 Peptide, zgc:55664 Peptide, ase1 Peptide, ASE1 Peptide, D7Ertd348e Peptide, protein regulator of cytokinesis 1 Peptide, protein regulator of cytokinesis 1a Peptide, protein regulator of cytokinesis 1 S homeolog Peptide, protein regulator of cytokinesis 1b Peptide, PRC1 Peptide, prc1a Peptide, prc1.S Peptide, prc1b Peptide, CNC07120 Peptide, prc1 Peptide, Prc1 Peptide
- Background
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This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.
Alias Symbols: ASE1
Protein Size: 195 - Gene ID
- 9055
- NCBI Accession
- NP_001254509
- UniProt
- H0YL53
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