Suppression of Tumorigenicity 5 (ST5) (Middle Region) Peptide
ST5
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ST5 products
- ST5 (Suppression of Tumorigenicity 5 (ST5))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KLSMSSIETA SLRDENSESE SDSDDRFKAH TQRLVHIQSM LKRAPSYRTL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- ST5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ST5 (Suppression of Tumorigenicity 5 (ST5))
- Synonyms
- zgc:91902 Peptide, wu:fc11b09 Peptide, si:ch211-208c6.1 Peptide, ST5 Peptide, DKFZp459D1230 Peptide, hts1 Peptide, p126 Peptide, dennd2b Peptide, DENND2B Peptide, HTS1 Peptide, 2010004M01Rik Peptide, 2610305K15Rik Peptide, suppression of tumorigenicity 5 Peptide, st5 Peptide, ST5 Peptide, St5 Peptide
- Background
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This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Alias Symbols: HTS1, p126, DENND2B
Protein Size: 717 - Gene ID
- 6764
- NCBI Accession
- NM_005418, NP_005409
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