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Numb Homolog (NUMB) (C-Term) Peptide

NUMB Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511897
  • Target See all NUMB products
    NUMB (Numb Homolog (NUMB))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    DRHTEVPTGT CPVDPFEAQW AALENKSKQR TNPSPTNPFS SDLQKTFEIE
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- NUMB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NUMB (Numb Homolog (NUMB))
    Synonyms
    C14orf41 Peptide, S171 Peptide, c14_5527 Peptide, Nb Peptide, NUMB, endocytic adaptor protein Peptide, numb homolog (Drosophila) Peptide, NUMB Peptide, Numb Peptide, numb Peptide
    Background
    The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.

    Alias Symbols: S171, C14orf41, c14_5527

    Protein Size: 456
    Gene ID
    8650
    NCBI Accession
    NM_001005743, NP_001005743
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