Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3) (C-Term) Peptide
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- Target See all KCND3 products
- KCND3 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GLRPNCKTSQ ITTAIISIPT PPALTPEGES RPPPASPGPN TNIPSIASNV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KCND3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KCND3 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3))
- Synonyms
- KCND3 Peptide, zgc:55306 Peptide, wu:fi06g01 Peptide, kv4.3 Peptide, K(v)4.3 Peptide, AW045978 Peptide, Kncd3 Peptide, Kv4.3 Peptide, KCND3L Peptide, KCND3S Peptide, KSHIVB Peptide, KV4.3 Peptide, kcnd3-A Peptide, xKv4.3 Peptide, potassium voltage-gated channel subfamily D member 3 Peptide, potassium voltage-gated channel, Shal-related subfamily, member 3 Peptide, potassium channel, voltage gated Shal related subfamily D, member 3 Peptide, potassium voltage-gated channel, Shal-related family, member 3 Peptide, potassium channel, voltage gated Shal related subfamily D, member 3 L homeolog Peptide, KCND3 Peptide, kcnd3 Peptide, Kcnd3 Peptide, kcnd3.L Peptide
- Background
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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.
Alias Symbols: KV4.3, SCA19, SCA22, BRGDA9, KCND3L, KCND3S, KSHIVB
Protein Size: 655 - Gene ID
- 3752
- NCBI Accession
- NM_004980, NP_751948
- UniProt
- Q9UK17
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