Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) (Middle Region) Peptide
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- Target See all STAM2 products
- STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
- Protein Region
- Middle Region
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QFSLISATIK SMKEEGITFP PAGSQTVSAA AKNGTSSNKN KEDEDIAKAI
- Characteristics
- This is a synthetic peptide designed for use in combination with STAM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
- Synonyms
- Hbp Peptide, STAM2A Peptide, STAM2B Peptide, 1200004O12Rik Peptide, 5730456G07Rik Peptide, BB145015 Peptide, stam2 Peptide, MGC52950 Peptide, zgc:103628 Peptide, signal transducing adaptor molecule 2 Peptide, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 Peptide, signal transducing adaptor molecule 2 S homeolog Peptide, STAM2 Peptide, Stam2 Peptide, stam2.S Peptide, stam2 Peptide
- Background
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The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
Alias Symbols: Hbp, STAM2A, STAM2B
Protein Size: 523 - Gene ID
- 10254
- NCBI Accession
- NM_019667, NP_005834
- UniProt
- O88811
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