Tumor Necrosis Factor alpha (TNF alpha) (C-Term) Peptide
TNF alpha
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TNF alpha products
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AVSYQTKVNL LSAIKSPCQR ETPEGAEAKP WYEPIYLGGV FQLEKGDRLS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNFA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
- Synonyms
- DIF Peptide, TNF-alpha Peptide, TNFA Peptide, TNFSF2 Peptide, RATTNF Peptide, Tnfa Peptide, tnf Peptide, TNF-a Peptide, TNFalpha Peptide, Tnfsf1a Peptide, TNFa Peptide, cTNF Peptide, Tnf-alpha Peptide, tnfa-like Peptide, TNF-ALPHA Peptide, dif Peptide, tnfa Peptide, xtnf Peptide, tnfsf2 Peptide, tnf-alpha Peptide, Cachectin Peptide, tumor necrosis factor Peptide, tumor necrosis factor b (TNF superfamily, member 2) Peptide, tumor necrosis factor alpha Peptide, tumor necrosis factor a (TNF superfamily, member 2) Peptide, TNF Peptide, Tnf Peptide, tnf Peptide, tnfb Peptide, tnf-alpha Peptide, LOC103694380 Peptide, tnfa Peptide
- Background
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This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Alias Symbols: TNF,TNFA,TNFSF2,
Protein Size: 233 - Gene ID
- 7124
- NCBI Accession
- NP_000585
- UniProt
- P01375
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