Deleted In Azoospermia 3 (DAZ3) (C-Term) Peptide
DAZ3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DAZ3 products
- DAZ3 (Deleted In Azoospermia 3 (DAZ3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PAYPNSAVQV TTGYQFHVYN YQMPPQCPVG EQRRNLWTEA YKWWYLVCLI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DAZ3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DAZ3 (Deleted In Azoospermia 3 (DAZ3))
- Synonyms
- pDP1679 Peptide, DAZ3 Peptide, DAZ2 Peptide, deleted in azoospermia 3 Peptide, deleted in azoospermia protein 3 Peptide, DAZ3 Peptide, LOC738636 Peptide
- Background
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This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat.
Alias Symbols: pDP1679
Protein Size: 486 - Gene ID
- 57054
- NCBI Accession
- NM_020364, NP_065097
- UniProt
- Q9NR90
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