CDC-Like Kinase 2 (CLK2) (C-Term) Peptide
CLK2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CLK2 products
- CLK2 (CDC-Like Kinase 2 (CLK2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FDFLKDNNYL PYPIHQVRHM AFQLCQAVKF LHDNKLTHTD LKPENILFVN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CLK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CLK2 (CDC-Like Kinase 2 (CLK2))
- Synonyms
- MGC53993 Peptide, hclk2 Peptide, clk2 Peptide, fb20c02 Peptide, si:ch211-81a5.7 Peptide, wu:fb20c02 Peptide, MGC131228 Peptide, hCLK2 Peptide, AU041688 Peptide, Tu52 Peptide, CDC like kinase 2 Peptide, CDC like kinase 2 S homeolog Peptide, CDC-like kinase 2a Peptide, CDC like kinase 2 L homeolog Peptide, CDC-like kinase 2 Peptide, CLK2 Peptide, clk2.S Peptide, clk2 Peptide, clk2a Peptide, clk2.L Peptide, Clk2 Peptide
- Background
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This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.
Alias Symbols: CLK2,
Protein Size: 499 - Gene ID
- 1196
- NCBI Accession
- XP_005276799
- UniProt
- P49760
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