Growth Factor Receptor-Bound Protein 2 (GRB2) (Middle Region) Peptide
GRB2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GRB2 products
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DFDPQEDGEL GFRRGDFIHV MDNSDPNWWK GACHGQTGMF PRNYVTPVNR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- GRB2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
- Synonyms
- GRB2 Peptide, grb2 Peptide, AA408164 Peptide, Ash Peptide, ASH Peptide, EGFRBP-GRB2 Peptide, Grb3-3 Peptide, MST084 Peptide, MSTP084 Peptide, NCKAP2 Peptide, wu:fb18e12 Peptide, wu:fb34e06 Peptide, zgc:73077 Peptide, growth factor receptor bound protein 2 Peptide, growth factor receptor-bound protein 2 Peptide, growth factor receptor-bound protein 2b Peptide, GRB2 Peptide, grb2 Peptide, Grb2 Peptide, grb2b Peptide
- Background
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The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene
Alias Symbols: ASH, Grb3-3, MST084, NCKAP2, MSTP084, EGFRBP-GRB2
Protein Size: 176 - Gene ID
- 2885
- NCBI Accession
- NM_002086, NP_002077
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