Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (N-Term) Peptide
MAP2K4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MAP2K4 products
- MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AAPSPSGGGG SGGGSGSGTP GPVGSPAPGH PAVSSMQGKR KALKLNFANP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MAP2K4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
- Synonyms
- JNKK Peptide, JNKK1 Peptide, MAPKK4 Peptide, MEK4 Peptide, MKK4 Peptide, PRKMK4 Peptide, SAPKK-1 Peptide, SAPKK1 Peptide, SEK1 Peptide, SERK1 Peptide, SKK1 Peptide, Sek1 Peptide, Serk1 Peptide, MKK4A-l Peptide, map2k4 Peptide, zgc:136500 Peptide, jnkk Peptide, mek4 Peptide, mkk4 Peptide, sek1 Peptide, jnkk1 Peptide, serk1 Peptide, xmek2 Peptide, mapkk4 Peptide, prkmk4 Peptide, 142758_at Peptide, CG9738 Peptide, CT27508 Peptide, D-MKK4 Peptide, DMKK4 Peptide, Dmel\\CG9738 Peptide, JNKK2 Peptide, Mpk4 Peptide, SEK1/MKK4 Peptide, dMKK4 Peptide, dMkk4 Peptide, hep Peptide, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 Peptide, ATMEK4 Peptide, ATMKK4 Peptide, F19C24.26 Peptide, F19C24_26 Peptide, MAP KINASE KINASE 4 Peptide, mitogen-activated protein kinase kinase 4 Peptide, MKK4B Peptide, zgc:194486 Peptide, mitogen-activated protein kinase kinase 4 Peptide, mitogen-activated protein kinase kinase 4a Peptide, MAP kinase kinase 4 Peptide, mitogen activated protein kinase kinase 4 Peptide, mitogen-activated protein kinase kinase 4b Peptide, MAP2K4 Peptide, Map2k4 Peptide, map2k4a Peptide, map2k4 Peptide, Mkk4 Peptide, MKK4 Peptide, map2k4b Peptide
- Background
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This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
Alias Symbols: JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1
Protein Size: 399 - Gene ID
- 6416
- NCBI Accession
- NM_001281435, NP_001268364
- UniProt
- P45985
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